分类： cc

　　According to the website of Heilongjiang provincial government on 24th, suifenhe city, Dongning City, Fuyuan City, Tongjiang City, Mishan City, Raohe County, Jiayin County, Luobei County, Aihui District and Xunke County are now declared as land border port cities according to the requirements of the State Council’s joint prevention and control mechanism for novel coronavirus epidemic.

　　In order to effectively control the risk of epidemic spread, from the date of announcement to March 15, 2022, you must have a negative nucleic acid test certificate within 48 hours when you leave the above port cities. Please ask the relevant personnel to seriously abide by the requirements of epidemic prevention and control, and cooperate with relevant departments and units to check the nucleic acid test certificate. If the epidemic prevention and control obligations are not fulfilled and the spread of infectious diseases is caused, they will bear corresponding legal responsibilities.

　　Hulin City, Sunwu County, Huma County and Mohe City will strengthen the implementation of epidemic prevention and control measures according to the above-mentioned land border port cities.

Original title: Guangxi CDC issued a health reminder in September to prevent diseases such as dengue fever and hand, foot and mouth disease.

    Pay attention to personal hygiene, do not pick or eat wild mushrooms.

    On September 5th, Guangxi CDC issued the September Health Reminder, telling the public to take precautions against dengue fever, monkeypox, hand-foot-mouth disease, other infectious diarrhea caused by norovirus, acute hemorrhagic conjunctivitis, imported malaria, novel coronavirus infection and other infectious diseases, as well as food poisoning. The doctor reminded us to pay attention to personal hygiene and do a good job in self-health monitoring.

   ● Dengue fever removes stagnant water to prevent Aedes mosquitoes from breeding.

    Song Xiaoling, a member of the expert group on medical treatment of infectious diseases in Nanning and director of pediatrics of the Fourth Municipal Hospital, said that dengue fever is an acute insect-borne infectious disease and a Class B infectious disease stipulated by China’s Infectious Diseases Law. There are two epidemic situations of dengue fever: local epidemic and imported epidemic.

    At present, the main vector of dengue fever is Aedes albopictus. The virus is transmitted to humans through mosquito bites. Mosquitoes usually get infected when they suck the blood of infected people. Infected mosquitoes can spread the virus all their lives, and a few can pass the virus to their offspring through eggs.

    "The incubation period of dengue fever is generally 3 to 14 days, and most of them are 5 to 8 days. Patients and recessive infected people are the main sources of infection, and patients are contagious from 1 day before onset to 5 days after onset. " Song Xiaoling said that when a sudden high fever rises to 39~40℃ within a day or two, accompanied by symptoms such as measles and hemorrhagic rash, it is necessary to consider whether you are infected with dengue fever and go to the hospital in time.

    The best way to prevent dengue fever is to remove stagnant water, prevent Aedes mosquitoes from breeding and avoid being bitten by mosquitoes.

    Song Xiaoling suggested that citizens should wear light-colored long-sleeved clothes and trousers when going out in the environment with deep grass and dense forests, and apply mosquito repellent or mosquito repellent drugs on exposed skin and clothes as much as possible; Try to avoid staying in the shade, grass and other outdoor darkness for a long time during the frequent occurrence of "spotted mosquitoes". At the same time, do a good job in cleaning the family environment.

   ● Hand-foot-mouth disease mostly occurs in infants under 5 years old.

    Hand, foot and mouth disease is an infectious disease caused by enterovirus, which mostly occurs in infants under 5 years old. It is mainly transmitted through fecal-oral route, followed by respiratory droplets.

    Nanning Maternal and Child Health Hospital is a designated treatment institution for severe hand, foot and mouth disease in Nanning. Based on the detection of coxsackie virus A16 RNA, enterovirus universal RNA and other commonly used viral nucleic acids, the hospital introduced a rapid detection of EV71-lgM antibody against hand, foot and mouth disease, and the results were obtained within one hour.

    Yan Yunying, director of pediatrics at Nanning Maternal and Child Health Hospital, said that according to clinical monitoring data, the number of cases of hand, foot and mouth disease has increased recently. There are more than 20 types of enteroviruses that cause hand, foot and mouth disease. Coxsackievirus A, Coxsackievirus A, Coxsackievirus B and Coxsackievirus 71 are the common pathogens of hand, foot and mouth disease, among which Coxsackievirus A16 (CoxA16) and Coxsackievirus 71 (EV71) are the most common.

    Doctors reminded that vaccination with EV71 vaccine can prevent hand, foot and mouth disease caused by EV71 virus and reduce the occurrence of severe cases and deaths.

    Pay attention to hand hygiene, especially wash your hands before touching your mouth and nose, before and after meals, after changing diapers or handling items contaminated by feces.

    Pay attention to environmental hygiene. Open the window regularly every day for ventilation, do a good job of cleaning and disinfection, clean the home environment regularly, especially clean and disinfect children’s tableware, clothes, toys and other items, and wipe and disinfect the surfaces of objects such as the floor, desktop, door handle and bed fence at home.

    Try to avoid taking children to places where people gather and the air circulation is poor.

    Parents should pay more attention to the health status of young children, and go to the medical institution for treatment in time in case of fever, rash (especially perianal rash) or oral herpes.

   ● Monkeypox is mainly transmitted through men who have sex with men.

    Monkeypox is a zoonotic disease caused by monkeypox virus infection, and people are generally susceptible. It is mainly spread through close contact with monkeypox cases, and articles contaminated with virus may also be infected with the virus.

    The main clinical manifestations are fever, rash and lymphadenopathy. Most cases have mild clinical symptoms, and the death cases are mainly people with low immunity such as untreated HIV-infected people.

    Since May 2022, the monkeypox epidemic has spread to many countries. Since June 2023, many provinces in China have reported the epidemic situation of monkeypox, which is mainly spread by men who have sex with men. Men who have sex with men are the key groups infected with monkeypox. Recently, some areas in Guangxi have reported the epidemic situation of monkeypox among men who have sex with men.

    Disease control experts reminded that key populations should strengthen self-protection, reduce high-risk behaviors, avoid close contact with people with suspected monkeypox symptoms, and do not share clothes, bedding and other daily necessities of suspected cases. Self-health monitoring should be done if there is a history of suspicious contact; Entry-exit personnel should pay attention to the information of monkeypox epidemic situation in destination countries and regions, and do not contact people with monkeypox-like symptoms, rodents, primates and other animals.

   ● Imported malaria Try to wear long trousers outdoors.

    Malaria is a blood parasitic disease caused by the bite of Anopheles mosquitoes, which is also called "cold fever", "malaria" and "malaria". Africa and Southeast Asia are highly endemic areas of malaria.

    Disease control experts remind you to do personal protection, especially outdoors, and try to wear protective clothes, such as long sleeves and trousers. Exposed skin can be coated with mosquito repellent. Pay attention to environmental sanitation, remove garbage, weeds, fill sewage pits, and do a good job in mosquito control.

    Before going abroad, you should know the epidemic situation of malaria and other diseases in the destination and make personal protection preparations; After returning from Africa, Central and South America and Southeast Asian countries, if you have symptoms such as chills, fever, sweating and fatigue, you should go to a regular hospital as soon as possible and take the initiative to inform you of your living history.

   Norovirus does not eat half-baked sea (water) products.

    Norovirus is an acute intestinal infectious disease, which has the characteristics of acute onset, rapid spread and wide coverage. It is mainly spread through food and water contaminated by patients’ feces, or through close contact. The epidemic situation mostly occurs in schools, kindergartens, nursing homes and other places where people gather. The most common symptoms are diarrhea, vomiting and nausea.

    Disease control experts remind people to pay attention to personal hygiene and wash their hands frequently, especially before and after meals and before food processing.

    Food should be fully heated before eating, tableware should be disinfected regularly, and eating out should try not to eat half-baked sea (water) products.

    After the ground or objects are polluted by patients’ vomit or excrement, the pollutants should be cleaned and disinfected immediately under the premise of personal protection.

   ● Don’t rub your eyes with dirty hands for acute hemorrhagic conjunctivitis.

    Acute hemorrhagic conjunctivitis, commonly known as "pink eye", is a highly contagious acute eye disease caused by enterovirus. Through contact, eye-hand-eye is the main route of transmission. The clinical manifestations are tingling, gritty foreign body sensation, burning sensation, photophobia, tears, eyelid edema and high congestion of eyelid and bulbar conjunctiva.

    Ophthalmologists remind us to pay attention to personal hand hygiene and eye hygiene, wash our hands often with soap, try not to rub our eyes with dirty hands, and develop the hygienic habit of dividing towels and basins.

    Strengthen the sanitary management and supervision of swimming pools, baths, barber shops and hotels.

    If there are patients with infectious acute conjunctivitis at home, their daily necessities such as towels and washbasins should be disinfected. Do not share towels, bath towels, eye cosmetics or personal eye care products.

   ● novel coronavirus should still adhere to personal protection when it infects the public.

    At present, the overall prevalence of infection in novel coronavirus is at a low level. The public should still adhere to personal protection and be the first person responsible for their own health.

    Please complete the vaccination as soon as possible for those who meet the requirements but have not been vaccinated, have not been vaccinated in the whole process and have not been vaccinated, especially for the elderly over 60 years old.

    Wear a mask scientifically and regularly, wash your hands frequently, often ventilate, cover your mouth and nose when coughing or sneezing, and try to avoid contact with fever personnel.

    Eat a healthy diet, quit smoking and limit alcohol, work and rest regularly, ensure adequate sleep, and exercise moderately according to your own situation.

    The elderly, children, key people with chronic diseases and pregnant women should stay away from people with fever and cough symptoms, do a good job in health monitoring, and seek medical advice in time if they have fever and other discomfort; Wear masks during the whole process of medical treatment, and try to avoid taking public transport.

   ● Prevent food poisoning and do not pick edible wild mushrooms.

    Continuous high temperature creates suitable conditions for bacterial proliferation, food is easy to rot and deteriorate, and the risk of microbial food poisoning increases. In addition, September is still the peak season for the growth of all kinds of wild mushrooms in Guangxi, and with abundant rain, poisonous mushroom poisoning incidents are prone to occur.

    Deng Shangqin, a health science expert in Guangxi and director of the dog injury clinic of the Fourth Hospital of the City, reminded not to deliberately purchase fresh rare mushrooms or mushrooms that are unknown or claimed to be new products. Parents should remind their children not to pick when they take them to play in the grass and Woods, in case the children grab something to eat or eat their hands without washing their hands after picking, resulting in poisoning due to mushroom poison on their hands. "Some poisonous mushrooms are very toxic. After picking, they are unintentionally crushed, and the oozing poisonous juice touches the hands. A few milligrams of mushroom toxin may lead to acute poisoning and even death." (Reporter Ye Wei)

　　At the beginning of August, Zhang Chenyang, a senior student in Tsinghua University, received a notice from the college that he would participate in the selection of the Young Students’ Basic Research Project (hereinafter referred to as the Young Students’ Project) of the Natural Science Foundation of China on August 22, and he could choose any topic as long as the basic research related to natural science was concerned, and the project cycle was one or two years.

　　As the most important funding channel for basic research in China, the National Natural Science Foundation of China (hereinafter referred to as NSFC) brought undergraduates into its talent funding system for the first time, which attracted attention. In late August, the National Natural Science Foundation of China held the first evaluation meeting of young students’ projects in Beijing and Hefei. As a pilot, outstanding undergraduates from eight universities including Peking University, Tsinghua University and China University of Science and Technology (hereinafter referred to as China University of Science and Technology) were recommended to participate in the interview.

　　China News Weekly learned that up to now, the evaluation and selection of this project has been completed, and those who pass the selection can get a research fund of 100,000 yuan. According to official website, the Intelligent Research Laboratory of the Chinese University of Science and Technology, an undergraduate student in the laboratory has received relevant funding. When the project was first announced, it once aroused doubts in the scientific community: Do undergraduates have enough ability to do scientific research?

　　Who can get funding?

　　Zhang Chenyang is an undergraduate of the first "Strong Foundation Program" in Tsinghua University, which was launched in 2020 to select students with excellent comprehensive quality or top-notch basic research. Shortly after entering school, Zhang Chenyang, with the encouragement of his tutor, tried to carry out a scientific research project in the field of ancient building restoration that he was interested in. He spent half a year researching and experimenting, and as the first author, published the research results of this project in the domestic core journal Journal of Geotechnical Engineering. This experience opened a new world for Zhang Chenyang. "This result made me very satisfied, and I began to feel that the process of doing scientific research and solving problems was very interesting, which was very different from learning in class."

　　During his school years, he participated in many projects to support undergraduate scientific research, such as Tsinghua University’s "Academic Research Promotion Plan for College Students" and "Spark Plan", and the national training plan for college students’ innovation and entrepreneurship. In July, 2021, after the extreme rainstorm in Zhengzhou, Zhang Chenyang decided to turn to the research on flood forecasting and early warning. This is also the theme of Zhang Chenyang’s application in this young student project.

　　Over the years, the Natural Science Foundation of China has built a funding chain for talent projects, including "excellent youth", "outstanding youth" and innovative research groups, but the funding targets are all scholars engaged in scientific research. Putting the talent funding port ahead is a new reform of the Natural Science Foundation of China this year.

　　In May this year, the NSFC had a preliminary idea. In June, Dou Xiankang, Party Secretary and Director of the NSFC, led a team to Tsinghua, Peking University and other universities for investigation. In an exclusive interview with China Newsweek at the beginning of July, Dou Xiankang mentioned that during their investigation, they noticed that there are indeed some undergraduates who have spare capacity in learning and have interest and talent in scientific research. He has also seen some students who have completed their four-year courses in just one and a half years, thus having more time to do research. Judging from the law of talent growth, early discovery and targeted training of outstanding young talents will help them stand out as soon as possible and make great progress in the future, and also provide "flowing water" for building a high-quality basic research talent team.

　　The speed of the project is beyond many people’s expectations. In July, the project for young students was formally established, and in August, the Natural Science Foundation of China organized a meeting review. "We completed all the evaluation work before the end of August, in order to complete the project establishment and funding in September, so that students can start the project at the beginning of the new semester and invest in the project research." Dou Xiankang said.

　　Dou Xiankang said that at present, the project is still in the pilot stage, and the Natural Science Foundation of China hopes that the scope will be smaller, so the model of "recommendation+evaluation" will be adopted, and all students participating in the evaluation will be selected by universities according to relevant requirements. At the same time, however, in order to provide excellent students with opportunities for training and support, there is no quota limit for judging, and applicants with excellent performance can get financial aid. On August 22nd, Zhang Chenyang went to the office building of NSFC to participate in the selection. He noticed that there were about thirty or forty students from Tsinghua and Peking University.

　　The selection of undergraduate programs is different from the projects of "Jieqing" and "Youqing" of the Natural Science Foundation of China. According to reports, in the evaluation of young students’ projects, students should show their projects within the specified 8 minutes and answer experts’ questions within the remaining 17 minutes. Dou Xiankang once mentioned to China Newsweek that there is no need for college students to present scientific research results like "Jie Qing", and the questions raised by some students may not be mature, but the judges can generally see whether the students have a solid scientific foundation and enthusiasm for science — — This is an essential quality for scientific research.

　　Pan Xin, Dean of School of Aviation Science and Engineering, Beihang University, is one of the experts in the evaluation of young students’ projects. He condensed the criteria for judging students into one: whether students have the ability to ask questions. In the question-and-answer session, he will discuss with the students why he did this topic. The question is raised by himself or his tutor. "Perhaps most students have jointly raised questions after discussion with their tutors. After all, they are still young and have to attend classes. It is not easy to do this in a short time in a brand-new field."

　　Pan Yi told China News Weekly that most of the students who participated in the evaluation were sophomores and juniors. He remembers that some students studied urban planning and management, used new tools to do big data analysis of regional economic heat, and evaluated regional economic vitality. "This is a social science topic, but it impressed me deeply. In the process of students’ migration from the field of partial management to the direction of mathematics and physics, new problems in cross-cutting fields were excavated." There is also a student who studies the stability of gravitational wave antenna device, hoping to solve the problems in the existing technology by designing new engineering and software.

　　In addition, unlike the previous project review, the Natural Science Foundation of China suggested that the judges discuss with the students by means of communication rather than defense, "to inspire and guide them as much as possible and stimulate their interest in scientific research". When Pan Yi communicates with these children, he can feel that they all have a good theoretical foundation, but they also need more and wider academic exchange opportunities.

　　When Zhang Chenyang applied for related scientific research projects before, he was mostly asked about the professional knowledge of the project, and the tutors in the school mostly communicated with him about the details of the plan. At the review site, seven or eight experts from the audience raised about 10 questions, including basic knowledge, research experience, scientific research plan, etc., and some teachers gave him suggestions on research ideas. "I want to study the early warning of mountain torrents in North China, and then spread the experience to the whole country. A teacher at the scene suggested that I can do experiments nationwide first, and then sum up good methods. This and my research are two kinds of ideas, which can give me some inspiration. "

　　In addition, we need to pay attention to how to select students who are really interested in scientific research, so that the young student project will not become the "hat" of undergraduates. According to Mu Rongping, a researcher at the Institute of Science and Technology Strategy Consulting of China Academy of Sciences, some talent funding projects have become "hats", which has nothing to do with the funding itself. The problem is that subsequent employers regard these funding as a precondition for talent admission or evaluation. Funding outstanding undergraduates to do scientific research may not be a prerequisite for sending graduate students, which may be helpful to the selection of talents for young students’ programs.

　　Can undergraduates do scientific research well?

　　In the evaluation team that Pan Yi participated in, the projects declared by 11 students were very difficult, "it is difficult to make a complete solution in a short time", but Pan Yi did not expect these students to publish several papers or patents two years later, or to push the research problems to a new height. In his view, the real value of the young student project lies in that students can receive the training of scientific research paradigm and be more firmly involved in scientific research in the future. Mu Rongping pointed out to China Newsweek that the establishment of this project by the Natural Science Foundation is also in line with the laws of scientific research. Students need to participate in basic research, attend more academic conferences, communicate with outstanding peers at close range, and improve their thinking ability in solving scientific problems.

　　According to reports, on August 21st, the day before the evaluation of young students’ projects, NSFC invited Pan Jianwei, an academician of China Academy of Sciences, Luo Yi, executive director of the Department of Chemistry and Physics of Chinese University of Science and Technology, and other scientists to give academic reports to the undergraduates who participated in the evaluation. Dou Xiankang said, "In the future, we will provide them with more opportunities to participate in comprehensive high-end scientists’ forums, hoping to inspire and guide them to embark on the road of scientific research by letting top scholars at home and abroad communicate face to face with outstanding undergraduates, making reports, talking about experiences and feelings."

　　Mu Rongping told China Newsweek that, according to the laws of scientific research, different disciplines are different, and many scientists at home and abroad have made outstanding achievements at a young age in basic theoretical disciplines such as mathematics and physics. At present, the young students’ program is still in the pilot stage, with a small number of students selected and a low amount of funding, which may not be as much as a large project of the Natural Science Foundation of China. It is a good attempt to select students who are really interested in scientific research, and the outside world can give more tolerance.

　　Pan Xin has more than ten years of teaching experience, and is also responsible for the teaching reform planning and scientific research development of the college. In his view, the young student program is a "flag" and signal, that is, the state attaches importance to the coordinated development of education, science and technology, and talents, which can guide more university administrators to think about talent training at the undergraduate level.

　　Pan Yi pointed out to China Newsweek that most of the courses at the undergraduate and postgraduate levels in domestic universities are imparting known knowledge. There are fixed class hours in one semester, and what to talk about in each class will be planned in advance, eventually teaching students a set of systematic knowledge. Only when students really enter a research topic can they begin to transition to exploring the unknown. He hopes that this process can be advanced.

　　As early as 2005, the famous "Qian Xuesen’s question" was put forward. Today, how to cultivate top-notch innovative talents is still a common challenge for China University. Pan Yi noticed that some undergraduates, even postgraduates, lack scientific research training, and it is difficult to write a paper that people can understand. In his view, China’s basic education, undergraduate courses and practical equipment in some universities are not bad, but in the postgraduate stage, there will be a clear gap between China and top foreign universities. In top foreign universities, most natural science courses are required to write papers or reports at the end of the class. Students need to think, investigate and explore the unknown on the basis of the classroom knowledge system, but most courses in domestic universities still test the known content.

　　Mu Rongping believes that what is more important behind the young students’ project is how colleges and universities can reverse the learning and thinking habits of undergraduates, and turn from memorizing answers to discovering and exploring problems. "The key to real scientific research is to see who can find the real problems".

　　Lu Xiaodong, a researcher at Peking University Institute of Education, has been paying attention to undergraduate research for many years. In his view, NSFC’s funding for undergraduates is not new, but there is a new funding channel. Over the past 20 years, many universities in China have been supporting undergraduates who have the ability to learn to participate in scientific research. The traditional impression that "doctor is the entry stage of scientific research" is actually a cognitive misunderstanding.

　　Take Peking University as an example. In 1998, Li Zhengdao set up a "political fund" to introduce the scientific research model of American research universities into China. Subsequently, Peking University established a set of management system with "research courses" as the core, and incorporated undergraduate scientific research into the regular curriculum. Relevant subsidies included "political fund", "president fund" and "Mao Yugang fund". According to the "research course" of Peking University, the applicants should be sophomores, and their GPA should rank in the top 30% of the college. At the same time, the standardized management of the course requires students to ensure that they invest enough time, and there are requirements for the mid-term and completion of the project.

　　Pan Wei introduced that since 2021, Beihang University has conducted pilot research classes for sophomores and juniors. Each pilot college will open a research class as an elective course, accounting for 2 credits, and requires key laboratories at or above the provincial level to invest certain experimental conditions to support students. Pan Yi mentioned that compared with the traditional classroom, the scientific research classroom is open, and students may be faced with the most cutting-edge science and technology in a certain field. They can do experiments, research or theoretical formula derivation. There is no standard answer to this process. The most important thing for students is to learn scientific research paradigm, cultivate the ability of literature research, independently design operable experiments and write experimental reports.

　　"We have been piloting for 3 years, and about 90% of the undergraduates of Beihang University have taken scientific research classes. I obviously feel that after the preliminary training, the level of graduation design has been significantly improved." Pan Yi told China Newsweek. Lu Xiaodong once met some undergraduates who quit halfway because of lack of interest when doing scientific research projects. There are also some students who have participated in short-term laboratory projects in different disciplines. Many teachers have found that these students are seriously involved in each project, and they gradually clarify the future research direction in the process, even if they do not produce visible research results, they are also very valuable.

　　Compared with China, foreign top research universities began to encourage undergraduates to do research earlier. As early as 2000, Lu Xiaodong went to the United States to inspect the management of first-class universities, focusing on undergraduate education at the University of California, Berkeley. As a research university, Berkeley attaches great importance to undergraduate scientific research, and even regards it as an important part of undergraduate education. Since the 1990s, the university has set up special funds to support undergraduates to do scientific research. In 1997, it set up an undergraduate research office to organize and serve students’ research. Besides providing some information about project application, it will also help students understand what research is, how to write project applications and draw up reports through lectures. In addition, Harvard University, Massachusetts Institute of Technology, California Institute of Technology and many other American research universities have set up relevant institutions and projects to support undergraduates to do scientific research.

　　The undergraduate stage is a critical period for the cultivation of academic aspirations. Lu Xiaodong noticed that many alumni of Peking University who have made their mark in academia or returned to school as teachers have participated in research courses at the undergraduate level if they look at their resumes. In 2023, Zhang Cheng, a professor at Fudan University School of Management, and others published an article "The Impact of Undergraduate Research Projects on Personal Research Career Development — — In a retrospective cohort study, the research career development of undergraduate students and graduates of Fudan University from 2000 to 2017 was investigated, and the final sample included 576 data. It is found that compared with students who have not participated in scientific research projects, the probability of undergraduates who have participated in related projects graduating from doctoral programs has increased by 14.1%, and the probability of choosing scientific research positions in formal jobs has also increased by 17.2%.

　　The article points out that the important reason is that early scientific research training promotes students’ understanding of scientific research and cultivates students’ self-confidence in this field. Zhang Cheng and others believe that the key is not simply to let students take part in teachers’ topics or simply to pursue the publication of articles, but how teachers guide students to complete scientific research tasks, achieve goals and constantly build confidence in this process.

　　Relevant research points out that domestic undergraduate research projects have been carried out for many years, but the overall start is late, the coverage is narrow, the implementation effect of different universities is uneven, and relevant policies still need to be improved. Lu Xiaodong observed that in the past years, some university administrators have also visited Peking University to investigate their experience. In his view, the most important thing is that school administrators and teachers should first change the concept that gradual learning at the undergraduate level and problem-centered learning triggered by undergraduate research do not conflict, but will promote each other. To support undergraduates in scientific research, colleges and universities should first straighten out this problem. Secondly, relevant experts believe that the integration of undergraduate scientific research into the formal curriculum will help reduce the conflict between students’ participation in scientific research and course learning.

　　In addition, experts say that domestic universities need to invest more resources in undergraduate research. In China, except for some top universities, most of the undergraduate research work is assigned to the Academic Affairs Office. The relevant teachers lack enough energy and time to organize undergraduate research, and some teachers lack understanding of undergraduate research training, so it is difficult to undertake detailed guidance. At the University of California, Berkeley, in order to support teachers to participate in students’ scientific research, teachers will receive project assistance and a small grant of $ 300~600 to partially pay for students’ research-related expenses.

　　How to motivate teachers to actively participate is very important. In Lu Xiaodong’s view, taking undergraduates to do research really requires teachers to invest more energy. Some colleges and universities can give priority to selecting some willing excellent teachers. Teachers should also think clearly about the value and significance of this matter. Undergraduate scientific research courses can play a real role in the process of cultivating top-notch innovative talents, but it is not achieved overnight.

　　(Zhang Chenyang is a pseudonym in the text)

　　Published in China Newsweek magazine, No.1110, September 25th, 2023.

　　Magazine title: Natural Science Foundation of China subsidizes undergraduates for the first time.

　　With the epidemic under control, the passenger flow in Taikooli, Chengdu slowly resumed photography.

　　"Encourage the implementation of a flexible working system of 4.5 days a week and 2.5 days on weekends." Since March, Jiangxi, Zhejiang and other places have taken measures to actively guide cadres and workers to go out for leisure holidays on weekends, in order to boost consumption, promote economic growth and reduce the impact of the COVID-19 epidemic on the economy.

　　On March 25th, Wang Qiyan, a professor at Renmin University of China and director of China Leisure Economy Research Center, said in an interview with Chengdu Business Daily-Red Star News reporter that the income of employees in government agencies, enterprises and institutions is relatively stable, and the flexible working system is pioneered by this group. It is undoubtedly a feasible practice to promote consumption and drive a wider range of consumer groups by increasing the supply of time. Su Hainan, a special researcher in china association for labour studies, is more cautious. He said that the first thing to do to resume production at present is to ensure safety and prevent the epidemic from rebounding.

　　Five years ago, a 2.5-day weekly holiday was introduced.

　　But the implementation effect is not ideal.

　　On March 19th, Jiangxi Provincial People’s Government issued "About laying a good ‘ Combination boxing ’ Notice to boost tourism consumption. " It is mentioned that all localities and units should optimize their work arrangements according to the actual situation. In the second quarter of this year, they will try out 2.5 days of flexible work and rest on weekends and actively guide cadres and workers to go out for leisure and vacation on weekends. The working hours reduced by flexible work and rest can be compensated by extending the length of other working days.

　　Recently, the "Implementation Opinions of the General Office of the People’s Government of Zhejiang Province on Boosting Consumption and Promoting Stable Economic Growth" issued by Zhejiang Province mentioned that it encourages the implementation of a 4.5-day flexible working week and supports qualified organs, social organizations, enterprises and institutions to implement the paid vacation system.

　　In fact, encouraging the implementation of flexible working system is nothing new. In the Opinions of the General Office of the State Council on Further Promoting Tourism Investment and Consumption issued in August 2015, it is mentioned that flexible work and rest are encouraged, and places and units with conditions can optimize and adjust summer work and rest arrangements according to the actual situation, creating favorable conditions for employees to go out for leisure and vacation on Friday afternoons and weekends. Since then, more than 10 provinces, including Hebei and Chongqing, have issued opinions to encourage flexible work and rest for 2.5 days, but after five years, the implementation effect is not ideal.

　　Why is it difficult to implement?

　　Experts say that labor efficiency is relatively low.

　　The reason is that Wang Qiyan, a professor at China Renmin University and director of China Leisure Economy Research Center, believes that in the final analysis, the labor efficiency is relatively low.

　　Regarding the voice on the Internet that "two weekends are difficult to implement, not to mention flexible working system", Wang Qiyan believes that if society wants to make progress, there will always be some people who have to sacrifice, such as those who stand at the forefront of science and technology. There are still some groups, because of the characteristics of the industry or the particularity of the occupation, who can’t reach the average rest standard, which is also a reality.

　　4.5-day flexible working system

　　How much effect does it have on stimulating consumption?

　　From the perspective of stimulating consumption, Su Hainan thinks that the effect is not necessarily great.

　　He said that industries with relatively high wages and relatively stable incomes are willing to spend if they are given more rest time under safe circumstances. But for many employees of small and medium-sized enterprises, especially migrant workers, the first consideration may not be how to spend, but how to earn money quickly and maintain a normal life.

　　Su Hainan suggested that consumption should be gradually restored while ensuring safety. In the process of restoring consumption, people must be isolated according to the relevant requirements and regulations of epidemic prevention, and retaliatory consumption in crowded places is not advocated, because there are still risks. "Don’t look at the possibility that the turnover has come up, but if there is another infection in Covid-19, it will be terrible."

() The business review of the Board of Directors in the first half of 2023 is as follows:

　　I. Main businesses of the Company during the reporting period

(a) the company’s main business and products

The company is the leading supplier of intelligent transportation platform solutions for expressways, trunk roads and urban transportation in China. The company’s main business includes three aspects: first, the smart traffic electronic toll collection business based on ETC, including ETC issuance and sales, electronic toll collection service business, etc., focusing on expanding the construction and operation of expressway and urban traffic toll collection and management systems; Secondly, the business of intelligent transportation operation management system based on cloud technology mainly includes system software development, comprehensive solutions and system technical services of intelligent transportation operation management; Third, the derivative business of smart transportation is mainly to build ecological scenes with "ETC+" as the core, integrate the life of vehicles such as refueling, road economy and car maintenance, and develop the ETC ecosystem business.

During the reporting period, there were no major changes in the company’s main business.

1. Intelligent transportation electronic toll collection service

The company’s smart traffic electronic toll collection business is mainly based on ETC, including ETC distribution and sales, electronic toll collection services, etc., focusing on the construction and operation of expressway and urban traffic toll collection and management systems.

ETC distribution business: The company increased the promotion of ETC distribution in offline outlets and cooperation channels, that is, online platforms, optimized the ETC product system, and greatly increased the circulation. During the reporting period, the company newly developed 908,000 ETC users, an increase of 88.77% over the same period of last year. By the end of June 2023, the number of ETC users of the company had reached 23.058 million, covering 30 provinces and cities across the country.

The company has accelerated its business layout, and has established business cooperation relations with 14 OEMs including Changan Automobile, Geely Automobile, Tesla, Weilai, Kia of yueda and Jaguar Land Rover. During the reporting period, the company added SMART elf car and Lotus car front-loading projects, which have been successfully launched. In addition, the company and () innovatively researched and developed ETC smart automobile glass, and realized ETC front-loading in the field of automobile production supply chain, laying a good foundation for the sustainable growth of ETC distribution in the future. At present, Changan Automobile Auchan and Fujian Benz brands have been realized. Users can be locked in advance through the ETC pre-installation mode, which will further enhance the national market share of ETC users.

Electronic toll service: With the popularization of ETC, the further improvement of payment rate and the development of new car pre-installation mode, ETC payment has gradually penetrated from expressway to car-related scenes such as parking, refueling and ferry ETC. At present, the ferry ETC payment business has reached cooperation intentions with 22 auto ferry operation platforms in Anhui, Zhejiang, Sichuan, Guangdong and other provinces. As a pilot unit of digital RMB for enterprises in Jiangsu province, the company took the lead in realizing the application of digital RMB payment in the province’s expressways and user travel services, and has now realized the digital RMB payment function of ETC service outlets, Tongbao APP and MTC lanes of some toll stations in the province. During the reporting period, the recovery of expressway toll flow increased significantly, which led to the rapid growth of the company’s electronic toll settlement amount, reaching 23.6 billion yuan in the first half of 2023, an increase of 32.02% over the same period of last year.

2. Smart traffic operation management system business

The company’s intelligent transportation operation management system business relies on cloud computing, big data, artificial intelligence, Internet of Things and other technologies to develop and maintain intelligent transportation systems, effectively supporting comprehensive transportation operation decision management and services, and focusing on three major business scenarios of intelligent transportation command and dispatch, operational services and integrated management. It has formed three major service themes of "smooth travel, high quality and smart speed" and six product systems of "dispatching, charging, maintenance, service, integrated management and digital intelligence", which have the leading level in China. Its main customers are government agencies related to transportation management, road and bridge enterprises and institutions, traffic police and other law enforcement units.

At present, the company has accelerated the digital transformation of intelligent transportation and deepened the integrated technology path of "cloud-network-edge-end", and has formed a number of intelligent transportation application products and comprehensive solutions with high technical content, strong profitability, scale and sustainability. In February, 2023, the company’s independent innovative products "AI video analysis cloud control platform", "ETC electronic fence", "cloud charging-robot" and "tunnel digital twin technology" appeared at the "Digital Traffic Control" innovative product launch conference in 2023. At present, the company’s scientific and technological products mainly include: dispatching cloud and other series of cloud control platform products, state-owned cloud, SD-WAN intelligent networking technical services, high-speed brain, AI video analysis cloud control platform, free cloud charging solution, charging robot, tunnel digital twin technology and cloud+high-speed intelligent service platform, etc. The relevant products are as follows:

(1) Scheduling Cloud

"Dispatching Cloud" is a real-time interactive cloud service platform based on the concept of "internet plus Traffic", with travelers as the center, relying on rich advanced technologies and services on the cloud, and built around the emergency handling of expressways, with full coverage of processes, all-round management and full participation of the society. At present, it has achieved large-scale commercial operation, and has been used in expressways and some trunk highways in Jiangsu Province, and extended to Guizhou, Henan, Hebei, Guangxi, Hunan and other provinces. In the first half of 2023, the project newly expanded some high-speed management units outside the province, as well as some industry customers such as traffic emergency management units in prefecture-level cities and county-level cities in the province. In the first half of the year, the business achieved an operating income of 36,948,800 yuan, an increase of 47.57% over the same period of last year.

(2) Toll Cloud

The "toll cloud" is an independent innovation technology such as license plate "cloud recognition", () processing and fault-tolerant path restoration, which intelligently analyzes multi-dimensional captured data, identifies, locates, tracks and warns "specific vehicles", and builds a toll auxiliary system with accurate accounting, online billing and real-time escape, providing strong support for toll inspection.

(3) State-owned assets cloud

The "state-owned assets cloud" platform promotes the deep integration of informatization and state-owned assets supervision business around the "three majors and one big" decision-making, property right registration and transformation, foreign investment, financing guarantee and performance evaluation, and realizes the digital transformation of state-owned assets supervision business from decentralization to centralization, supervision information from isolation to sharing, management quality and efficiency from plane to three-dimensional, and supervision process from afterwards to real-time. During the reporting period, the project won the bid for the "Digital State-owned Assets" supervision platform project of Yancheng State-owned Assets Supervision and Administration Commission, achieving a breakthrough in state-owned assets projects at the prefecture level. Up to now, the platform has been applied in Jiangsu State-owned Assets Supervision and Administration Commission, Yancheng State-owned Assets Supervision and Administration Commission, China Communications Construction Co., Ltd. and other provincial state-owned enterprises such as (), Eastern Airport and Suliang Group.

(4) Internal control cloud

"Internal Control Cloud" is a reusable and customizable full-process digital management software service product for customers. This product uses the concept of flattening and great collaboration to finely manage and control the internal office processes in real time, and changes manual supervision into process supervision and data supervision. Through this product, the processes of information disclosure, document handover, supervision, procurement, salary, contract, meeting, payment, business trip, car use and duty are visualized and managed in a streamlined way, thus realizing the digitalization of organizational structure and process coordination, and greatly improving the office efficiency and management benefits of customers. At present, it has been widely used in expressway operation and management units such as Jiangsu and Shanxi.

(5) Conservation of clouds

"Maintenance Cloud" takes routine road inspection and maintenance as its core function, and realizes closed-loop road maintenance business management integrating maintenance plan, task assignment, inspection, disease reporting, construction measurement, assessment and statistical analysis, which promotes the transformation of experience management into a programmed and standardized management mode and further improves the efficiency and quality of maintenance management. This product has been applied in Guizhou Expressway and Xuzhou national and provincial trunk highways. Relying on the maintenance cloud, the reporting efficiency of expressway diseases under the jurisdiction of Guizhou Expressway Group increased by 3 times, the inspection efficiency increased by 4 times, and the accuracy of disease identification reached over 92%. In the first half of the year, the business achieved an operating income of 5,004,000 yuan, an increase of 65.61% over the same period of last year.

(6)SD-WAN intelligent networking technical services

"SD-WAN Intelligent Networking Technology Service" adopts two-way Internet broadband access, and undertakes the functions of safe and stable data transmission of various services from local to cloud. It solves the problems of long construction period, high cost, insufficient network accessibility and difficult data aggregation of traditional networks, greatly reduces the management difficulty, improves the network quality, ensures the stable bearing of expressway toll collection, communication and other services, and realizes cost reduction and efficiency increase. "SD-WAN networking technology" has achieved full coverage of 46 road sections, 95 pairs of service areas, 430 toll stations and 3,500 lanes in Jiangsu road network, supporting data transmission of more than 30 digital services.

(7) high-speed brain

Through the deep integration and exploration of blockchain technology and transportation industry, "High-speed Brain" has established an autonomous and controllable digital infrastructure, expanded and built a credible data space and value network oriented to the transportation industry ecology, realized the collection, gathering and sharing of multi-factor scenes, full business processes and pan-high-speed ecology, solved the problems of incomplete data gathering, unreliable sharing and transmission, difficult support for business collaboration and difficult establishment of digital ecology, and made overall consideration of the road smooth work by digital means to effectively realize high-speed. In the first half of the year, the above projects have not yet generated income, and it is expected that business income will be generated in the second half of the year.

(8)AI video analysis cloud control platform

"AI video analysis cloud control platform" is based on multi-source heterogeneous data fusion processing, AI video image algorithm evaluation and analysis, rule engine machine governance, business adaptability deep learning optimization and other technical links, and applies the self-developed "AI square" to construct the event monitoring early warning data that forms automation, visualization and fits the traffic application scene after intelligent identification, data fusion, algorithm analysis, multiple governance and training and learning. The platform can detect traffic accidents, abnormal parking, foreign body scattering, vehicle congestion, vehicle retrograde and other abnormal conditions in real time, and give an alarm prompt in real time. After application, it can greatly improve the highway traffic capacity and the ability to deal with accidents and incidents quickly. The test results show that compared with the traditional event discovery method, the intelligent early warning can be carried out 20 minutes in advance on average through the cloud control platform. The cloud control platform has been applied in East Expressway, Suhuaiyan Expressway and Nanjing-Hangzhou Expressway, and it is expected to be put into use in the second half of the year and generate business income.

(9) Free Cloud Charging Solution

The construction of "Free Cloud Charging Solution" focuses on "charging robot" and provides an overall solution for highway "free cloud charging", which improves the overall adaptability of toll station functions and reduces the construction cost, and realizes the full decoupling, data integration and online business of the charging system, and realizes the functions of accurate online charging, intelligent real-time audit, synchronous settlement verification and efficient special handling based on cloud big data. At present, a comprehensive charging system software with functions of charging, check-in and auditing has been formed, as well as family hardware products that are highly adapted to it, such as charging robot, digital economy big screen, fog lamp integrated equipment, grating vehicle type recognition integrated machine, integrated intelligent hurdle machine, ETC antenna and controller and license plate recognition camera. At present, the solution has been applied in 14 toll stations, such as (), Ningjingyan Expressway, Yanjiang Expressway, Suhuaiyan Expressway, Lianxu Expressway, Nanjing-Hangzhou Expressway and East Expressway, and 50 toll robots and 344 other family-owned equipment in toll lanes have been deployed. The production environment test shows that the solution can greatly improve the efficiency of expressway toll collection. It is estimated that each toll lane can save 2-3 toll collectors and greatly reduce the cost of expressway operation and management. It is expected that the free cloud charging solution will be widely applied in Jiangsu road network in the second half of the year.

(10) Tunnel digital twin technology

Based on the two management objectives of "safety" and "smoothness" of tunnels, "tunnel digital twin technology" sets up a "virtual and real bridge" for the integrated operation and management of roads and tunnels, and creates a "Jiangsu model" for the intelligent management of tunnels. This technology can not only realize the real-time presentation of all dynamic and static elements, but also directly operate the feedback on the twin page, which makes the tunnel management more intelligent, effectively solves the operational problems of the largest underwater tunnel in China, such as high requirements for real-time online operation monitoring, difficult emergency rescue, difficult equipment management and control, high requirements for preventive and active management and control, and greatly improves the tunnel operation efficiency. This technology has been demonstrated in Taihu Tunnel, the longest underwater tunnel in China, and has been applied in Yangzhou City Tunnel Group and Tongzi Tunnel in Guizhou.

(11) Cloud+high-speed intelligent service platform

"Cloud+high-speed intelligent service platform" is a digital high-speed traffic police business cloud platform built around the service management and law enforcement of high-speed traffic police under the trend of "one network for all roads", adhering to the concept of "multi-party joint management, resource joint use and service joint work". The platform can realize the sharing of bad weather data, from passive disposal afterwards to active prevention in advance and active response in the event, which can effectively promote the high-quality development of Jiangsu high-speed traffic safety management and travel service guarantee. The platform has been applied in Jiangsu Provincial Traffic Police Corps.

3. Smart Transportation Derivative Business

The derivative business of smart transportation is mainly the ETC ecosystem business related to car life. Relying on the advantages of the number of ETC users and the volume of data, we will build ecological scenes with "ETC+" as the core, integrate user services such as high-speed traffic, parking, refueling, road economy and car maintenance, innovate business models, create derivative services of ETC ecosystem, and provide customers with integrated car life services.

During the reporting period, the company actively promoted the construction of ETC ecosystem and innovated the business model of smart transportation derivative business. Adhering to ETC’s strategy of "getting off the road and entering the city", ETC’s smart parking business pioneered the overall solution of "electronic fence" technology in China, effectively solving the problem of "leakage" in traditional parking mode, which has been built and operated in more than 20 cities and counties such as Suqian City, Wuxi City, Taizhou City, Nanjing Gaochun City and Suzhou Taicang City. In the first half of the year, 863 new parking lots were signed up and 767 were put into operation. By June 2023, ETC’s smart parking business had been put into operation. Carry out actions to improve the efficiency of ETC polymerization refueling process and optimize the refueling experience of refueling workers and customers. During the reporting period, the transaction volume of polymerization payment refueling was 787 million yuan, an increase of 41% compared with the second half of 2022; Focusing on the consumer demand of car-related consumer products and car owners’ daily necessities, the company built a "1+1 +2" business service matrix of "Tongbaoxiaodian+TongbaoTik Tok Live+2 Mobile Consumer Terminals" to build an exclusive business service platform for ETC users and provide personalized and customized consumer services; Providing supply chain collaborative services such as customer acquisition channels, product operation strategy optimization and risk management measures for banks, factoring companies, truck transportation platforms and other cooperative institutions, the business has grown rapidly. In the first half of the year, the derivative business of smart transportation achieved an operating income of 13,055,800 yuan, a year-on-year increase of 138.01%.

(II) The industry in which the company is located during the reporting period.

1, the company’s industry

The company’s main business belongs to the field of intelligent transportation business. It mainly provides software development, overall solutions and technical services by analyzing the information system requirements and system design of customers’ business needs, and develops intelligent transportation electronic toll collection business, intelligent transportation operation management system business and intelligent transportation derivative business.

2, the industry development and development trend

Intelligent transportation is an important area of new infrastructure. In recent years, the state has successively issued a large number of policies and measures to support the development of intelligent transportation, and the intelligent transportation industry is in a period of rapid development. The national transportation power strategy, the new infrastructure policy and the Tenth Five-Year Plan have continuously promoted the digital transformation of the transportation industry. From top-level design to supporting implementation, the policy dividend of the smart transportation industry has been continuously released, and the two-wheel drive of policy demand has boosted the smart transportation industry to usher in a sustained and prosperous development, accompanied by deep excavation of data capabilities, which has driven the industry’s efficiency to continue to improve. The recent core policies of the smart transportation industry include the digital economy policy, the new infrastructure policy, the traffic power policy at the national level, and the relevant policies of the Ministry of Transport, the Ministry of Public Security, the Ministry of Industry and Information Technology and other relevant ministries and commissions in transportation planning, traffic safety and order management, and intelligent network connection.

The intelligent transportation industry has been growing for a long time. Due to the unbalanced level of economic development and technological development in different regions of China, the investment and construction of intelligent transportation management system in China are uneven in various regions, and the intelligent transportation business also presents certain regional characteristics. According to the forecast of Yiou think tank, the smart transportation market in China will reach 10.6 trillion yuan by 2030, with a broad growth space. It is expected that the technologies related to intelligent transportation will continue to mature in the future, and the intelligent layout of vehicles, roads and clouds will continue to improve, and the market will show a steady growth trend. Policy promotion, customer demand and technological progress have accelerated the transformation of the transportation industry from informationization to digitalization, and data has gradually become one of the core production factors. The characteristics of interconnection and data element empowerment have prompted the intelligent transportation industry to move towards "cloud-network-edge-end" integrated technology integration and life-cycle value operation. The market share of Smart Exchange began to concentrate on the head enterprises with data and algorithm capabilities and in-depth understanding of the industry.

In the field of electronic toll collection for smart transportation, electronic toll collection for expressways in China started relatively late, and began to be implemented on a pilot basis in 2005. In recent years, the General Office of the State Council, the National Development and Reform Commission and the Ministry of Transport have successively issued policies to encourage and support the development and application of ETC, and the industry has achieved rapid development. At present, ETC is the most important toll collection method for toll roads in China. With the continuous improvement of the national network toll collection mechanism, the continuous expansion of application scenarios and the continuous improvement of technical level, the application of ETC is moving towards the 2.0 stage. According to the statistics of the Ministry of Public Security, by the end of June 2023, there were 328 million cars in China and 16.2 million new energy vehicles. In the first half of 2023, there were 16.88 million newly registered motor vehicles nationwide, a year-on-year increase of 1.9%; According to the relevant data released by china automobile dealers association, in the first half of 2023, the national second-hand car transaction volume was 8.77 million. Overall, there is still much room for development in this subdivision.

3, the company’s industry status

After years of development, the company has actively expanded the national market by virtue of its industry-leading technical advantages, product advantages and operational advantages, and has now become a leading supplier of intelligent transportation platform solutions for expressways, trunk roads and urban transportation.

(1) The first listed company in the industry and the national benchmark for the reform of state-owned enterprises.

In September, 2022, the company was successfully listed on Shenzhen Stock Exchange, becoming the first listed company in the ETC distribution service industry in China, laying a solid foundation for making better use of the capital market to promote the high-quality development of enterprises. The company is a national "science and technology reform demonstration enterprise", Jiangsu "small double hundred" comprehensive reform enterprise and Jiangsu mixed ownership reform enterprise, making full use of the reform policy and capital market advantages, and has established a sound corporate governance structure and market-oriented operation mechanism. After being evaluated as "excellent" enterprises by the State Council State-owned Enterprise Reform Office for two consecutive years in 2020 and 2021, the achievements of reform practice were evaluated as "benchmark" enterprises (20/159) in 2022, which became a model for the reform of state-owned enterprises.

(2) The total number of 2)ETC issuing users ranks among the top three in China.

The company is the only ETC distribution service organization in Jiangsu Province, taking the lead in realizing Internet distribution in the industry and realizing the nationwide distribution of distribution business. By the end of June 2023, the company had developed about 23.058 million ETC users nationwide, ranking the top three in the country in terms of total users. The company now has a strong level of software technology, and has established a relatively perfect user service system and channel operation system.

(3) The scale of "ETC+" businesses such as parking lots has grown rapidly.

As the only main implementation unit of the provincial demonstration area of ETC smart parking in China, the company is based in Jiangsu and has a nationwide layout, deepening the integration and development of high-speed dynamic smart transportation and urban static smart transportation, adhering to the ETC strategy of "going down to the city", and initiating the overall solution of "electronic fence" technology for ETC smart parking business in China, and promoting the application of ETC charging system in large transportation hubs, as well as smart parking lots in different scenes such as hospitals, universities, commercial complexes, tourist attractions and residential properties. In the field of smart transportation derivative business, the company has built a comprehensive ecosystem of smart transportation and continuously innovated its business model, which has great potential for future development.

(4) The business of intelligent transportation operation management system is in the leading position in the industry.

In the field of intelligent transportation operation and management, the company is in a leading position in the industry, closely following the management and service requirements of the transportation industry, and has successively developed a series of cloud control products, taking the lead in realizing the "cloud" of business in the industry, promoting the national leading level of Jiangsu’s high-speed intelligence, and has been applied in highway networks in 20 provinces across the country such as Guizhou, Hebei and Henan, realizing the national market layout of business. The cloud series products developed by the company based on the cloud network convergence architecture have realized the convergence and sharing of data resources and effective collaboration of business applications, enhanced the emergency command and decision-making ability of traffic operation management, improved the efficiency and safety level of road network operation management, and provided all-round and accompanying information services for the public, constantly promoting the intelligent and digital transformation of expressway industry.

Second, the core competitiveness analysis

(A) technical advantages

1. Establish a "self-centered, self-controllable, open, integrated, flexible and efficient" R&D system to create the source of key core technologies.

The company is committed to the innovation and development in the field of digital transportation, constantly improving its scientific research capabilities, establishing a scientific research and development system that is "self-centered, self-controllable, open, integrated, flexible and efficient", focusing on three business scenarios of intelligent transportation command and dispatch, operation service and comprehensive management, and has successively launched a number of scientific and technological innovations that "lead the direction of the industry, promote transportation reform and subvert the traditional model". Many scientific and technological innovations are at an advanced level in the industry and have formed a "smooth line" By June 2023, the company had acquired 291 intellectual property rights, including 23 invention patents, 73 utility model and appearance patents and 195 software copyrights. During the reporting period, the company obtained the "AAA Credit Enterprise" certification, completed the ISO27001 information security management system certification, and passed the ISO9001 quality management system, ISO20000 information technology service management system and CMMI five-level software capability maturity management system certification. The company led the preparation of the group standard "Jiangsu ETC Smart Parking Construction Specification", which has passed the outline review of Jiangsu Comprehensive Transportation Society; Leading the preparation of the local standard "ETC Smart Cloud Parking Management Construction Specification", which has passed the pre-examination of Jiangsu Provincial Department of Transportation.

2. Build a "1+1+1+N" intelligent ecological alliance and build an ecological system of digital transportation scientific research cooperation.

The company has built a "1+1+1+N" intelligent transportation ecological alliance and continuously expanded the "circle of friends" for scientific research cooperation. Strengthen exchanges and cooperation with authoritative scientific research institutions, solve all kinds of "stuck neck" technical problems, and achieve important scientific research and technology research. Strengthen cooperation with well-known colleges and universities, and carry out academic, theoretical and practical multi-dimensional systematic research on key projects. Sign a talent training plan with the software laboratory of Nanjing University, carry out talent introduction and training, and build a software testing and data application laboratory; Cooperate with Nanjing University of Posts and Telecommunications to carry out research on traffic knowledge maps and other fields. Strengthen cooperation with well-known industrial Internet enterprises, realize cross-industry, cross-field and inter-departmental collaborative development mechanism, and jointly build an ecosystem of digital transportation scientific research cooperation. Cooperate with (), Huawei, Tencent Cloud, Shangtang Technology, Qingyun Technology and China Communications Hyde to set up six laboratories, namely, toll station digital twin joint laboratory, 5G edge equipment joint laboratory, industry application center joint laboratory, high-definition video cloud application joint laboratory, smart view joint laboratory and road and meteorological digital early warning joint laboratory. The company has become a strategic partner with () and ZTE to promote the innovative development of the transportation industry in terms of new technologies, new models and new applications.

3, build new infrastructure, rich achievements in scientific and technological innovation.

In line with the strategic deployment of the national "new infrastructure" and the requirements of the times, we will further improve the new digital transportation infrastructure technology architecture based on "cloud control", "smart network" as the transmission mode, "smart edge" as the calculation carrier, "smart end" as the IOT unit, and "cloud-network-edge-end" as a whole, so as to promote the digital transformation and intelligent upgrade of expressway network, and promote the automatic driving. The company is recognized as a national high-tech enterprise, a top 10 digital transportation enterprise in Jiangsu Province, a key software enterprise encouraged by the state, a leading enterprise in the high-quality development of modern service industry in Jiangsu Province, an engineering technology research center in Jiangsu Province, an engineering technology research center for smart high-speed travel service and operation in Jiangsu Province, an engineering technology research center for smart transportation cloud services in Jiangsu Province, and a Samsung Shangyun enterprise in Jiangsu Province. The core technology product "Dispatching Cloud" was selected as "Excellent Case of Digital Transformation of State-owned Enterprises in China"; "Digital Innovative Application of Highway Collaborative Command and Dispatching Cloud Service Platform" was selected as a typical case of digital transformation of listed companies in China; "SD-WAN Full Coverage Networking" was selected as an excellent case of "Cloud Computing Standards and Open Source Promotion Conference" and included in "Top Ten Symbolic Projects of Smart Jiangsu"; "Cloud-network-edge-end" digital new infrastructure project and "ETC ecological operation platform" project won the second prize of China traffic investment and financing innovation; "Jiangsu High-speed Brain" was selected as a pilot demonstration project for the development of big data industry in Jiangsu Province; "Jiangsu Expressway’s Integrated Digital Governance and Intelligent Decision-making Platform for Building, Managing and Supporting Services" is included."Smart Jiangsu Key Project" and "Top Ten Symbolic Projects of Smart Jiangsu", and won the "2023 China Expressway Informatization Annual Selection-Best Product" award from China Highway Society; "Eye on the Road-Video AI Intelligent Platform" was selected as an innovative product of artificial intelligence integration in Jiangsu Province in 2022; The project "Research and Demonstration on Key Technologies of Expressway Cloud Audit Management" was selected as the second prize of Science and Technology Award of Jiangsu Comprehensive Transportation Society.

(B) Market application advantages

In the field of intelligent transportation segmentation, the company has always been deeply involved in the Jiangsu market, and actively expanded the national market by virtue of industry-leading technological advantages, product advantages and operational advantages. By the end of June 2023, the company had developed about 23.058 million ETC users nationwide, covering 30 provinces and cities across the country, with the total number of users ranking among the top in the country. With "ETC+" as the core, a comprehensive intelligent transportation ecosystem in vertical areas such as ETC+ highway, parking, refueling, supply chain service and road economy has been built.

In the business field of intelligent transportation operation management system, based on the advantages of independent technology, after years of operation, the company has rich experience in project implementation and achieved a lot of excellent project results. The company actively implements the development strategy of digital economy, develops and promotes digital technology products, and has formed mature business models and products, which have been extended to 20 provinces across the country, providing intelligent solutions for the "new infrastructure" of national transportation. Rich product market application experience provides a strong competitive advantage for the company to expand its business and further develop in the future.

(C) Strategic synergy advantages

The company makes full use of the advantages of resources, scenes and business in Jiangsu Road Network to create a "test field" and "incubation area" for innovation and creation, promote the incubation and transformation of scientific and technological innovation achievements in the internal market, form mature experiences and models, export them to the national market, and create a smooth internal and external dual-cycle industrial development system; Establish capital and business cooperation relations with China UnionPay, (), Nantong Transportation Group and Tencent, and exert strategic synergy with the advantages of resources, technology and scenarios of each shareholder; Establish good and close cooperative relations with more than ten financial institutions such as Industrial and Commercial Bank of China, Bank of China and China Construction Bank, further promote the integrated development of consumption scenarios and financial services, and enhance the depth and breadth of the company’s services in the field of "transportation+"; Vigorously carry out scientific and technological innovation exchanges and strategic cooperation, and establish strategic partnerships with well-known enterprises such as China Telecom, Huawei, Hikvision, ZTE, Tencent Cloud, Shangtang Technology, Qingyun Technology and China Communications Hyde to promote the innovative development of the transportation industry in new technologies, new models and new applications; Strengthen cooperation with well-known universities such as Nanjing University, Southeast University and Nanjing University of Posts and Telecommunications, and jointly set up a "think tank brain" with scientists, industry experts and college professors to carry out academic, theoretical and practical multi-dimensional systematic research on key projects and form a reproducible, producible and exportable guiding scientific research plan.

(D) Management advantages

Through years of reform and development, the company has established a complete and effective management system and mechanism, the governance structure is more perfect, the decision-making mechanism is more efficient, the market-oriented selection and employment mechanism is more flexible, the market-oriented incentive and restraint mechanism is more perfect, and the kinetic energy of scientific and technological innovation is effectively stimulated. At present, the company has a professional, mature and stable core team with rich industry experience, technical experience and management experience, which can seamlessly connect the whole process of customer demand, product design, R&D and maintenance services, and has excellent business execution and product realization capabilities. The company’s R&D team has always followed the forefront of industry and technology development, followed the direction of industry development, and constantly learned from industry development, integrating advanced product development and design ideas into the company’s products, providing solid support for the company’s development.

In the reform of state-owned enterprises, the company has become a benchmark for the reform of state-owned enterprises, and the reform practice of "Demonstration Action of Scientific Reform" has been selected as an excellent case of the State Council SASAC; The three-year action case of state-owned enterprise reform was selected as a typical case of Jiangsu SASAC. The company was once again selected as one of the national "scientific reform enterprises" and launched a new round of scientific reform action (2022-2025), which will make full use of the new round of reform policies and opportunities, continue to deepen the reform of the system and mechanism, further stimulate the vitality of enterprise development and promote the high-quality development of enterprises.

Iii. Risks faced by the Company and Countermeasures

1. Risk of policy change

With the sustained and rapid development of China’s economy, the demand for residents’ life and travel is increasing day by day, and the smart transportation industry has developed rapidly. Since the State Council’s "Government Work Report" in 2019 proposed that the provincial toll stations of national expressways should be basically abolished within two years to realize fast toll collection without stopping, the State Council, the National Development and Reform Commission and the Ministry of Transport have successively issued a series of policies to encourage the related construction of non-stop toll collection, creating a good environment for the rapid and healthy development of enterprises in the industry.

Although the medium-and long-term planning of the country has clearly focused on the development of the intelligent transportation industry, and the supporting policy of the country for non-stop charging has a strong practical basis and social needs for a long time, if the government’s supporting policies for intelligent transportation related fields, especially ETC technical routes, are adjusted or the pace of implementation is uncertain in the future, the company’s operating performance will be affected to some extent.

In view of the above risks, the company will pay close attention to policy changes, strengthen strategic layout, optimize business structure, increase R&D investment and scientific and technological innovation, actively expand new commercial application fields and business models, enhance the company’s anti-risk ability and sustainable development ability, and maintain its leading position in the industry.

2. Industry competition intensifies risks.

As one of the important fields of intelligent transportation, ETC industry is becoming more and more market-oriented, and the market competition pattern is in a stage of rapid change. At present, the company is the only authorized ETC issuer in Jiangsu Province. Although it has established a perfect online distribution channel and can realize nationwide ETC issuance, it has not yet established an offline ETC issuance service network outside Jiangsu Province. Due to factors such as local car owners’ habit of choosing to handle ETC business in their permanent residence, there is still great competitive pressure for the company to handle ETC issuance business outside Jiangsu Province. If there are major changes in the future industry policies, industry norms and market competition pattern, the company’s ETC issuance and sales market share is at risk of being seized by competitors.

In the field of intelligent transportation business, although the company took the lead in developing a series of products such as cloud control platforms in the industry, which have the first-Mover advantages in products and services and have a high market share, on the one hand, there are companies engaged in similar businesses in all provinces, which have certain market resources and regional service advantages in the local area. In the future, with the improvement of technology and service capabilities of such companies, the company will face greater market competition when further exploring the national business market; On the other hand, the relatively high profit margin of the smart transportation industry also attracts other enterprises to enter the industry through infiltration, merger and reorganization, industrial transformation, etc., and there is a risk of intensified competition in the industry in the future.

In view of the above risks, the company will seize the strategic opportunity of digital economy countries, strengthen industry research and market insight, use the deep understanding of smart transportation industry and business, improve the accuracy of understanding user needs and the foresight of market trends, give play to the advantages of technological innovation, enrich product development matrix, and provide customers with all-round solutions; Improve the marketing promotion system, vigorously expand the national product market, expand brand influence, consolidate and increase market share, and enhance market comprehensive competitiveness; Strengthen industry exchanges and technical cooperation, actively build a diversified ecosystem of partners, and build a "moat" with continuous R&D and innovation capabilities.

3, technology update risk

The development of intelligent transportation industry needs to effectively integrate advanced information technology, data communication and transmission technology, electronic sensing technology, electronic control technology and computer processing technology on the basis of perfect infrastructure, so as to establish a real-time, accurate and efficient intelligent transportation operation and management system that plays a role in a wide range and in all directions. This industry has the characteristics of fast technology update. If the company can’t accurately grasp the technology development trend of the industry and follow up the direction of technology research and development in the future, or the speed of product research and development can’t match the demand of the industry and competent departments for technology update, the company’s market competitiveness and sustainable development will be adversely affected.

In view of the above risks, the company will pay close attention to the dynamic development of technologies in emerging fields, dynamically optimize and adjust the technology planning and research and development direction of new technologies according to the changes in market demand and technology development, strictly manage the research and development and application process, and strengthen the collaborative development workflow of technologies and products; At the same time, the company will continue to increase investment in R&D, strengthen the construction of technical personnel, introduce outstanding technical personnel and integrate internal R&D forces, improve the incentive mechanism for R&D personnel, actively promote the transformation of technological R&D achievements, maintain the overall leading edge of technical teams, and consolidate the leading position in the industry in major business-related technologies.

　　Xinhua News Agency, Beijing, October 27th Title: Eliminate the pain of medication, the worry of vaccine and the trouble of "medical trouble" — — China speeds up medical and health legislation to "prescribe medicine" for chronic medical problems.

　　Xinhua News Agency reporter Tian Xiaohang

　　The problem vaccine cases are shocking. Fake drugs and high-priced drugs make patients look forward to "medicine", and frequent "medical troubles" hurt "doctors" and "patients". In order to get rid of these persistent medical problems, the draft law on basic medical care and health promotion, which was submitted to the National People’s Congress Standing Committee (NPCSC) for the second review a few days ago, puts forward that the personal safety and personal dignity of medical and health personnel should not be violated, a whole-course drug traceability system should be established, and a planned vaccination system &hellip should be implemented; … Safeguarding the rights and interests of doctors and patients with the rigid constraints of law.

　　Crack down on "medical trouble": the practice place of medical and health institutions is a public place.

　　On September 22nd, three obstetricians and gynecologists in Peking University First Hospital, including He Yingdong, were beaten by the patients’ families while on duty, and the problem of "medical trouble" was once again pushed to the forefront of public opinion.

　　According to the White Paper on Physicians’ Practice in China released by the Chinese Medical Doctor Association in early 2018, only 34% of physicians have never personally experienced violent medical injuries. In recent years, from "medical trouble being punished" to multi-department joint punishment, the state has frequently cracked down on "medical trouble", but it is still difficult to eliminate the phenomenon of violent injury to doctors.

　　The second draft of the draft law on basic medical care and health promotion proposes that the personal safety and personal dignity of medical and health personnel are inviolable and their legitimate rights and interests are protected by law. The practice place of medical and health institutions is a public place providing medical and health services, and no organization or individual may disturb its order.

　　"In order to maintain the normal medical order and the professional rights and interests of medical and health personnel, and ensure that patients have a good medical environment and medical rights, it is necessary and urgent to clarify the legal attributes of medical and health institutions." Deng Yong, an associate professor in the Department of Law of Beijing University of Chinese Medicine, believes that defining the practice places of medical and health institutions as public places is conducive to the better connection between the law and the punishment law for public security administration, and the public security organs can enforce the law more effectively to crack down on "medical troubles" according to law.

　　To reduce violent injuries to doctors, in addition to protecting the rights and interests of medical and health personnel, it is necessary to reduce the contradiction between doctors and patients in a multi-pronged manner to prevent problems before they occur.

　　Protect the rights and interests of patients. The second draft of the draft puts forward that citizens have the right to informed consent on matters related to illness, diagnosis and treatment plan, medical risks, medical expenses and so on when receiving medical and health services. Citizens have the right to voluntarily participate in clinical trials of drugs and medical devices and other experimental medical research according to law and enjoy informed consent.

　　Strengthen the management of medical institutions. The second draft of the draft proposes that the state should establish a medical dispute prevention and handling mechanism to properly handle medical disputes and maintain medical order. Medical and health industry organizations and medical and health institutions shall strengthen the education of medical ethics for medical and health personnel. Medical and health personnel shall not take advantage of their positions to ask for, illegally accept property or seek other illegitimate interests.

　　"It is necessary to really get rid of profit-seeking factors such as taking medicine to support doctors, over-medical treatment, over-examination and setting income-generating indicators for hospitals, so that public medical care can return to public welfare." Deng Yong said that the fundamental solution to the problem of "medical troubles" depends on continuously deepening the reform of the medical and health system, effectively solving the problems of difficulty and high cost of medical treatment, and improving the salary and treatment of medical and health personnel and patients’ medical experience.

　　Let the masses use the rest assured drugs: establish the whole process traceability system of drugs

　　Selling more than 30 kinds of fake anticancer drugs to 30 provinces in China, a box of drugs can make a maximum profit of 10 thousand yuan, and the amount involved exceeds 10 million yuan … … A huge case of manufacturing and selling counterfeit drugs in Shenzhen exposed the defects in the field of drug quality and safety supervision in China.

　　In order to let the people use the rest assured drugs, the second draft of the Basic Medical Care and Health Promotion Law has a special chapter, which makes detailed provisions on the related issues of "drug supply guarantee".

　　It is clear from the second draft that the state will improve the supply capacity of essential drugs, strengthen the quality and safety supervision of essential drugs, and ensure the fair, accessible and rational use of essential drugs. The state improves the drug supply guarantee system, establishes a coordination mechanism for drug guarantee, and coordinates the research and development, production, circulation, use, evaluation and supervision of drugs to ensure the safety, effectiveness and accessibility of drug use by citizens.

　　Enterprises produce "medicine for conscience" and pharmacies don’t sell "medicine for black heart", so people can use "medicine for rest assured". The risk of drug quality and safety exists in the whole life cycle of drug research and development, production, circulation, management and use. To this end, the second draft of the draft proposes that the state should strengthen the management of drugs and establish a whole-course traceability system for drugs to ensure the quality and safety of drugs.

　　"The whole process of traceability can realize that the source of drugs can be traced, the destination can be traced, and the responsibility can be investigated." Yan Jianzhou, a project researcher at the National Drug Policy and Pharmaceutical Industry Economic Research Center of China Pharmaceutical University, said that in the event of drug quality and safety problems, the whole traceability system can also control the scope of influence, recall related products, find out the reasons in time, and protect the rights and interests of the people.

　　The phenomenon of winning the bid at ultra-low price in the bidding of essential drugs also brings hidden dangers to the quality of drugs. Experts generally believe that this kind of behavior seriously affects the normal supply of clinical drugs and has a greater degree of social harm. Therefore, we should increase the punishment and increase the illegal cost.

　　To this end, the second draft of the draft clearly States that the state strengthens the supervision and management of centralized drug procurement, and bidders participating in drug procurement bidding shall not bid at a price lower than the cost. The second draft review also strengthened the legal responsibility of bidders who participated in drug procurement bidding at a price below the cost in violation of the law.

　　In recent years, there are frequent local and structural shortages of clinically necessary drugs such as protamine and mitomycin. How to eliminate the pain of "waiting for medicine to save lives"

　　The second draft of the draft proposes that the state publishes the list of essential drugs, and dynamically adjusts the list of essential drugs according to the clinical application practice of drugs, changes in drug standards, and the new listing of drugs.

　　"Dynamic adjustment can make the newly approved drugs with significantly improved efficacy and reasonable price enter the catalogue in time to ensure the accessibility of patients." Yan Jianzhou said that drugs whose clinical effects no longer have comparative advantages or have quality and safety problems can also be transferred out of the catalogue in time through dynamic adjustment, so that the safety of patients’ medication is guaranteed.

　　Resolving vaccine anxiety: the state implements a planned vaccination system.

　　Changchun Changsheng Biotechnology Co., Ltd. illegally produced rabies vaccine and other vaccine cases, which exposed loopholes and potential risks in the supervision of vaccine production and use, and caused continuous concern of public opinion.

　　In order to dispel the public’s doubts and worries, the second draft of the Basic Medical Care and Health Promotion Law proposed that the state implements a planned vaccination system, and citizens have the right and obligation to receive the national immunization program vaccine according to law. Vaccines used for vaccination should be produced in strict accordance with good manufacturing practice, meet the national drug standards, and ensure safety and effectiveness.

　　The second draft of the draft also proposed that the state should implement a vaccination certificate system for children. When children enter nursery schools, nursery institutions and schools shall examine vaccination certificates, and if they find that they have not been inoculated according to the national immunization plan, they shall report according to law, and cooperate with relevant units to urge their guardians to replant in time after children enter nursery schools and schools.

　　Deng Yong believes that raising some contents of vaccine-related administrative regulations and rules into law can realize the scientificity, completeness and rationality of legislation; Defining the responsibilities of all parties in the process of vaccine use in law will also help to avoid the occurrence of vaccine fraud and adverse reactions.

　　The reporter learned that the revised draft of the Drug Administration Law, which was submitted to the National People’s Congress Standing Committee (NPCSC) for deliberation for the first time a few days ago, also listed separate provisions to strengthen the supervision of vaccines and other special drugs. For example, in the process of vaccine development, production, circulation and vaccination, information technology should be used to collect and retain traceability information. The holder of the marketing license of the vaccine shall be insured in accordance with the relevant provisions of the state.

　　Vaccines are involved in many places in the revised draft of the Drug Administration Law. For example, vaccines, blood products, narcotic drugs, psychotropic drugs, and toxic drugs for medical use may not be commissioned for production, except in cases where the drug supervision and administration department of the State Council stipulates that the production can be commissioned. The pharmaceutical supervisory and administrative department shall focus on supervision and inspection of biological products such as vaccines. In addition, the revised draft comprehensively increases penalties, and clarifies that six types of illegal acts, such as the production and sale of vaccines belonging to counterfeit drugs and inferior drugs, will be severely punished within the statutory scope.

A few days ago, Chezhi. com learned from relevant channels that HarmonyOS Zhixing will launch a variety of new cars in 2025, including the M8 that has already exposed the patent application map. It is reported that the new car will be unveiled before the end of the year, and the official listing and delivery time will wait until 2025.

In terms of appearance, it is not difficult to see through the declaration map that the new car will provide two front face designs to choose from. Among them, the first patent application scheme adopts ring lamp group; The second declaration scheme is a relatively traditional through-lamp group design. The overall outline is close to the M9 style of the world, creating a relatively strong gas field. In detail, the top of the vehicle in both declaration schemes is equipped with lidar.

The vehicle side transition is relatively straight and regular, which is conducive to improving the utilization of the interior space. Presumably, it is expected to adopt 6-seat and 7-seat layouts. By naming, it is not difficult to see that the product positioning of the new car will be between M7 and M9.

At present, 3D renderings based on patent application drawings have also spread on the Internet. Although there are few details, the overall outline and highlight design are basically displayed. It is rumored that the M8 will lead a new generation of family-style design language. Compared with the two SUV models owned by HarmonyOS Zhixing, the visual perception is more scientific and luxurious.

Interior spy photos do not have too much reference significance, because of the high degree of camouflage, it is difficult to see the specific design details. The M8 will continue to be equipped with the extended range power system, but the specific parameters have not been announced yet. For more news about the new car, the car quality network will continue to pay attention to and report.

　　On April 28th, the first quarterly report of 2022 released by Shouyao Holdings recently triggered a heated discussion, in which the operating income was only 707 yuan, down 99.98% year-on-year. Some investors teased whether the unit "10,000 yuan" was misspelled. Yinshi Finance reporter noticed that there was market news that the staff suspected of holding the first drug revealed in a pharmaceutical industry exchange group that the above income was "selling a second-hand incubator". Regarding the above-mentioned news about the sale of incubators, the relevant person of the Securities Department of Shouyi Holding told reporters that the specific business situation will be verified with the Finance Department, which may indeed be like the news that the reporter saw. At the same time, it said that the company is mainly engaged in the research and development of new drugs, including anticancer drugs and type II diabetes. At present, the fastest product is clinical phase II/III, and there are no commercial products approved for listing. At present, the company does not have main income. I hope that everyone will pay more attention to the company’s research and development progress. The reporter learned from the industry that pharmaceutical companies are in a special situation. Article 5 of the science and technology innovation board Listing Standard allows pharmaceutical companies to declare IPOs when their core products enter the second phase of clinical trials. Therefore, it is not uncommon for products to be commercialized and their revenues to be low. (Yinshi Finance)

　　Read more

　　Shouyao Holdings released its first quarterly report after listing: its revenue in a single quarter was 708 yuan, and its market value was less than 3 billion yuan.

　　On April 27th, Shouyao Holdings -U(688197,SH) (hereinafter referred to as Shouyao Holdings) released its first quarterly report after listing. In the first quarter of this year, the company’s revenue was only 707.96 yuan and its net profit loss was 50.6623 million yuan. The listed companies’ revenue less than that of 1000 yuan in a single quarter also triggered a heated discussion among investors.

　　However, there are indeed special reasons for Shouyao Holdings to hand over such transcripts. Up to now, the company’s products are in the research and development stage, and there are no drugs approved for marketing. However, on the other hand, the lack of performance support makes it difficult for the share price of Shouyao Holdings to perform well. On the face of it, the company’s share price broke on the day of listing and has continued to fall since then. Up to now, the total market value of the company’s shares has been less than 3 billion yuan, which is different from the "estimated market value of not less than 4 billion yuan" required by the fifth set of listing standards in science and technology innovation board.

　　Single-quarter loss expansion

　　According to the first quarterly report of Shouyao Holdings in 2022, the company achieved a revenue of 7.0796 yuan, down 99.98% year-on-year, and a net profit loss of 50.6623 million yuan. In the first quarter, the company’s R&D investment totaled 46.1181 million yuan, a year-on-year increase of 40.40%. In the first quarter of last year, the revenue of Shouyao Holdings was 4 million yuan and the net profit loss was 34.6864 million yuan. In the second, third and fourth quarters of last year, the company’s net profit lost 34.9066 million yuan, 34.323 million yuan and 41.0053 million yuan respectively. In contrast, the company’s losses in the first quarter of this year have expanded.

　　Previously, Shouyao Holdings stated in the listing announcement that, in combination with the actual operating conditions, it is estimated that the company will realize an operating income of 0,000 yuan to 2 million yuan from January to March, which is mainly affected by factors such as the progress of cooperative drug research and development; With the increase of R&D investment, it is estimated that the company will still be in a loss state from January to March, with a net profit of-50 million yuan to-30 million yuan. The actual performance of the company in the first quarter is basically in line with the above forecast.

　　"Where did you earn 707.96 yuan? Sell waste paper and old office furniture? " "The revenue is not enough for my utilities" and "Will this quarterly report be a bit too ridiculous" … Investors in the stock bar have some complaints about this.

　　For the sharp decline in performance in the first quarter of this year, listed companies said that the company’s revenue from drug cooperative development has not yet reached the settlement period during the reporting period, and the revenue from drug cooperative development has not been confirmed in this period, a decrease of 4 million yuan compared with the same period of last year.

　　On the afternoon of April 28th, the reporter of national business daily called the Secretary-General’s Office of Shouyao Holdings. Relevant persons said that at present, the company is still in the research and development stage, and there is no real product listing and commercial sales, which makes the company not form a large-scale revenue.

　　Shouyao Holdings is a small molecule innovative drug company in the clinical research stage, and its research and development pipeline covers key tumor indications such as non-small cell lung cancer, lymphoma, hepatocellular carcinoma, pancreatic cancer, thyroid cancer, ovarian cancer, leukemia and other important disease fields such as type II diabetes. Previously, the company also clearly stated in the prospectus: "At present, the company has no products listed, and there is no drug sales revenue, and there is still great uncertainty about whether and when the products can be listed. The company will not be able to generate product sales revenue in a certain period of time in the future."

　　It is reported that the core products SY-707 and SY-3505 of Shouyao Holdings are ALK (anaplasticlymphomakinase) inhibitors; Among them, SY-707 belongs to the second generation ALK kinase small molecule inhibitor, which has been approved by National Medical Products Administration Drug Evaluation Center, and can apply for conditional approval for marketing after the results of Phase II clinical trials reach expectations.

　　For the research and development progress of the company’s products, the above-mentioned people of Shouyi Holdings believe that the progress of new drug research and development cannot give a clear timetable, after all, it is accompanied by greater research and development risks; However, the company will disclose the R&D progress at the corresponding time node according to the relevant requirements of science and technology innovation board.

　　The market value has shrunk significantly.

　　It is worth mentioning that Shouyao Holdings was not listed by virtue of its performance conditions. "The company is an innovative drug research and development enterprise that applies the fifth set of listing standards." The company once said so. The fifth set of listing standards in science and technology innovation board is: "The estimated market value is not less than 4 billion yuan, and the main business or products need to be approved by the relevant state departments, with a large market space. At present, it has achieved phased results and obtained a certain amount of investment from well-known investment institutions. Enterprises in the pharmaceutical industry need to obtain at least one second-phase clinical trial approval for a first-class new drug, and other enterprises that meet the positioning of science and technology innovation board need to have obvious technical advantages and meet the corresponding conditions. "

　　Judging from the short-term performance of the first drug holding stock after listing, the company has drifted away from the market value of 4 billion yuan.

　　In March this year, Shouyao Holdings completed the listing and issuance, and the company issued 37.18 million shares, with the issue price of 39.90 yuan per share, the total raised funds was 1.483 billion yuan, and the net raised funds was 1.374 billion yuan. On March 23rd, the company’s stock was officially listed in science and technology innovation board.

　　However, the share price of Shouyao Holdings broke on the first day of listing, once rebounded to 35.98 yuan/share, and finally closed at 32.11 yuan/share. Since then, the company’s share price has also continued to decline. As of the close of April 28th, the company’s share price closed at 17.97 yuan/share, with a total market value of 2.672 billion yuan.