Hunan province: the innovative idea of "going out to sea" of traditional Chinese medicine

  "This is the 10 th province I have visited in Zimbabwe and the 11 th free clinic I attended." On December 2, 2023, the 20th batch of Zimbabwean medical teams from China (Hunan) where Hu Sha is located came to Manikaran Province, 300 kilometers away from Harare, the capital, to carry out free health clinic activities. The acupuncturist from Hunan Province is currently the head of the propaganda team of the medical team. She told reporters: "This year’s free clinic plan is ‘ January 1st province ’ At present, it has traveled to all provinces in Zimbabwe, with a total of more than 6,000 consultations and a journey of over 7,000 kilometers, which is unprecedented in the medical work of aiding Tianjin. "

  At present, Chinese medicine has spread to 196 countries and regions, and its international influence is expanding day by day. It is understood that Hunan Province is one of the important sending provinces of China’s medical assistance to Africa. The medical assistance to Africa began in 1973 and has gone through 50 years. On November 24th, 2023, Li Xiaosong, Party Secretary and Director of the Health and Wellness Committee of Hunan Province, said at the press conference that Hunan Province launched the overseas dissemination of Chinese medicine, and set up three overseas Chinese medicine centers in Zimbabwe, United Arab Emirates and Pakistan to promote Huxiang Chinese medicine to "group out to sea". What are the characteristics of overseas exchanges and cooperation of traditional Chinese medicine in Hunan Province, and what achievements have been made?

Hu Sha (first from right) and his colleagues are giving acupuncture therapy to patients.

Hu Sha (first from right) and his colleagues are giving acupuncture therapy to patients.  

  Changing "blood transfusion" into "hematopoiesis" and promoting the cultivation of international Chinese medicine talents in two ways

  The 20th batch of Zimbabwean medical teams from China (Hunan) has 11 people, including 2 Chinese medicine practitioners. Chinese medicine services mainly rely on China — Zimbabwe Chinese Medicine Acupuncture Center (referred to as "Chinese Medicine Center"). The center is located in the largest public hospital in Harare, the capital of Zimbabwe — — Parirenyatwa Hospital is the first Chinese medicine clinic in Zimbabwe and the largest Chinese medicine acupuncture center in southern Africa. Chinese medicine center provides acupuncture, massage, cupping, physical therapy, traditional Chinese medicine and other special treatments for local people and overseas Chinese.

  "Our clinic has been scheduled for next April, and Chinese medicine is very popular among local people and overseas Chinese." Hu Sha said that with the efforts of two groups of medical teams for more than two years, there are currently 12 treatment beds in the Chinese medicine center, with an average daily outpatient volume of over 50 people. It is worth mentioning that in addition to TCM diagnosis and treatment, the medical aid team in Tianjin is also responsible for the training and teaching of doctors and training local Chinese medicine acupuncture talents in Zimbabwe. Xiao Wenming, deputy director of the Hunan Provincial Administration of Traditional Chinese Medicine, said at the press conference that Hunan Province ensured that Chinese medicine experts participated in the selection of foreign aid medical team members. While providing acupuncture and other Chinese medicine services, we trained 10 Chinese medicine talents for Zimbabwe.

  In addition, in actively participating in the construction of the "Belt and Road" and spreading Chinese medicine culture, Xiao Qinghua, vice president of the First Affiliated Hospital of Hunan University of Chinese Medicine, said that the hospital has established Dubai Hospital, the first affiliated hospital of Hunan University of Chinese Medicine, in the United Arab Emirates. Six medical staff have obtained Dubai qualification and accumulated 55,000 services.

Tuden Basang (middle) is doing wrist hand consultation for patients under the guidance of tutor Zhang Wei.

Tuden Basang (middle) is doing wrist hand consultation for patients under the guidance of tutor Zhang Wei.

  At the same time of "going out to sea in groups", a group of "foreign Chinese medicine practitioners" came to Hunan, and Thupten Palzang (English name) was one of them. He is a general practitioner in a secondary hospital in Bhutan. He has been a doctor for ten years and is now studying acupuncture and massage in the First Affiliated Hospital of Hunan University of Chinese Medicine. The reason why he came to China to study Chinese medicine, Tuden Basang said: "I chose to study Chinese medicine, especially acupuncture, because Chinese medicine has unique advantages in treating certain diseases, such as chronic diseases, pain and health preservation. Chinese medicine pays attention to holism and regards patients as a whole, not just ‘ Headache cures the head and foot pain cures the foot ’ 。” Tudenbasan said that after graduation, he will integrate the Chinese medicine technology he has learned into clinical diagnosis and treatment, and provide patients with more alternative treatment options.

  Cheng Bo, secretary of the Party Committee of the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, said at the press conference that in promoting the cultivation of international Chinese medicine talents, the hospital has carried out 346 clinical internships in Chinese medicine for more than 10 countries and provided online and offline Chinese medicine training and Chinese medicine cultural experience for 300 countries.

  Building a platform to promote international cooperation in the whole industry chain of traditional Chinese medicine

  "China and Africa have great demand for further cooperation in promoting trade in traditional Chinese medicine, cultivation, development and research of medicinal materials." Zhu Wei, deputy director of acupuncture and tuina rehabilitation department of Hunan Hospital of Integrated Traditional Chinese and Western Medicine (affiliated hospital of Hunan Institute of Traditional Chinese Medicine), was the captain of the 19th batch of Zimbabwean medical teams in China (Hunan), and returned to China after a one-year foreign aid in March 2023. He said that there are many high-quality plants and medicinal materials in Africa. Through expositions and forums, relevant officials and entrepreneurs from African governments visited Hunan, and many people showed great interest in Chinese medicine and acupuncture in China. Further strengthen international cooperation, promote Chinese medicine products to enter the African market, and build a new highland of global Chinese medicine industry. According to reports, the China-Africa Chinese Medicine Cooperation Forum held at the end of June 2023 was the "first show" at the China-Africa Economic and Trade Expo and will become a permanent project of the China-Africa Economic and Trade Expo.

  In February 2023, the General Office of the State Council issued the Implementation Plan of Major Projects for the Revitalization and Development of Traditional Chinese Medicine, which mentioned in the plan for the promotion of international trade in traditional Chinese medicine that the export base of traditional Chinese medicine services should be built with high quality, new formats and new modes of export of traditional Chinese medicine services should be explored, and internationally renowned brands of traditional Chinese medicine services should be cultivated.

  It is understood that in March 2022, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine was selected as the national export base of traditional Chinese medicine services and became the first national export base of traditional Chinese medicine services in Hunan Province. Zhu Zhenhua, deputy secretary of the Party Committee and president of the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, said that in order to provide Chinese medicine services to overseas people, the hospital established the International Medical Department in 2018, which was the first high-end medical service platform for public Chinese medicine hospitals in Hunan Province to provide special medical services for patients at home and abroad, with 7,736 outpatient visits in 2022 and 1-mdash in 2023; The number of outpatient visits in November was 9432. In 2023, the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine was approved as the "National International Cooperation Base of Traditional Chinese Medicine", and gradually exported the technology, products, talents, culture and brands of traditional Chinese medicine to countries around the world.

  In addition, in terms of building a platform, Hunan Province took the lead in initiating the establishment of a collaborative development alliance for the entire industrial chain of Chinese medicine in Hunan, Jiangxi, Guangdong, Hong Kong and Macao. Taking development and innovation as the leading factor, the Alliance explores a new path of high-quality development of traditional Chinese medicine for mutual benefit and win-win in three provinces and two regions, cultivates a global highland of traditional Chinese medicine industry, and builds a "demonstration zone of coordinated development of Hunan, Jiangxi, Guangdong, Hong Kong and Macao" with high quality, providing new help and new impetus for the reform and development of traditional Chinese medicine in China.

  Build a bridge to help Chinese medicine go public overseas.

  It is reported that China’s current exports of traditional Chinese medicine products show a steady growth trend. 1-mdash in 2023; In June, China’s exports of traditional Chinese medicine products reached US$ 2.915 billion, up by 3.63% year-on-year. The export of traditional Chinese medicine products has become an important variety of medicine "going out".

  As a major province of traditional Chinese medicine, Hunan Province has a unique resource endowment and humanistic foundation. The planting area of traditional Chinese medicine in the province exceeds 4.5 million mu, and it has nearly 5,000 kinds of traditional Chinese medicine resources, ranking fourth in the country and first in central China. The output value of the whole industrial chain of traditional Chinese medicine exceeds 100 billion yuan. Facing the difficulties and pain points of "going out" of Chinese medicine enterprises, Hunan Province has given targeted solutions.

  As the Chinese patent medicine has not yet formed a global unified scientific standard system, the access conditions and supervision methods in various countries are not uniform. On the one hand, the demand for international trade is rising, and on the other hand, the international standards for related varieties are lacking, which hinders Chinese medicine from going overseas to some extent. Standardization has become one of the key issues for Chinese medicine to "go global".

  On May 12, 2022, the International Organization for Standardization (ISO) officially released the international standard of Chinese Medicine-Sinomenine, which is the first ISO standard for Chinese herbal medicines developed in Hunan Province, filling the gap in the field of international standard formulation of Chinese herbal medicines in Hunan Province, and will better promote Chinese herbal medicines in Hunan Province to the world and benefit human health.

  "For Chinese medicine products to go to sea, relying on enterprises themselves to open up overseas markets has high risks and uncertainties, and the cost is uncontrollable." As a national key Chinese medicine enterprise and a key high-tech enterprise in Hunan Province, Jiuzhitang, a century-old brand, can’t "go global" without the innovative linkage of large and small environments.

  Zhang Liangbin, the financial director of Jiuzhitang Group, talked about "going out to sea" and was quite touched. "For Jiuzhitang, to open overseas markets, we chose to cooperate with overseas export industrial parks supported by the government, and chose the Brazilian market mainly because Brazil is a major overseas partner of Guangdong-Macao Chinese Medicine Industrial Park." In addition, Zhang Liangbin said that Chinese medicine products need to be excellent in order to open overseas markets, and product quality and curative effect are crucial. As a time-honored Chinese brand, Jiuzhitang also adheres to the concept of innovation in inheritance and development in innovation. At present, the research and development of classic prescriptions of traditional Chinese medicine are being carried out, and at the same time, the existing products are being re-evaluated and the indications are being expanded. The second is to have good local distributors, and the third is to have professional licensed pharmacists to train distributors according to the efficacy and applicable population of each product, so that overseas friends can know, understand and accept it through professional marketing team, and gradually fall in love with Chinese medicine products and culture.

  At present, seven proprietary Chinese medicine products produced by Jiuzhitang Co., Ltd. have obtained the import and business license of the National Health Supervision Bureau of Brazil (ANVISA), which indicates that these products are qualified to be sold in the Brazilian market and can be legally sold in hospitals, clinics, pharmacies and other medical institutions in Brazil in the form of prescription drugs.

  Xiao Wenming, deputy director of Hunan Provincial Administration of Traditional Chinese Medicine, said that at present, 16 fist products of traditional Chinese medicine in Hunan Province have been registered and listed overseas, and will continue to communicate and coordinate with relevant departments in the future to speed up the overseas registration process of Chinese medicine enterprises, reduce the registration cost of enterprises, and further promote the overseas listing of Chinese medicine products in Hunan Province. (Proofread Fan Lijun)

How to finish online courses quickly

  Now is the internet age, and many elective courses in universities offer the choice of online courses, which allows students to choose online courses or offline courses freely. So,How to finish online courses quickly? The following will be introduced to you.

How to finish online courses quickly

  Step 1, download and install an old version of the roaming browser;

  Step 2, open the web page of the online course, enter the settings of the browser, and set the mandatory extreme speed mode in the advanced settings;

  Step 3, click on the online course video you selected;

  Step 4, put the mouse in the video frame, and a horse icon will appear in the upper right corner of the video frame;

  Step 5: Move the mouse to the icon and select Fast Forward.

  The above is the answer about how to finish the online course quickly, hoping to help everyone.

How does Youku client open local video/open online video?

Method for opening local video/online video by Youku client:

  1. If you check the associated file button "Play *.flv file with Youku client for Windows" when installing Youku client, double-click the local file to play it with Youku client.

  2. If the associated file button is not checked, you can select a video file and right-click "Open with Youku Client" to play it.

  3. When the video is not played, enter the play page, and you can open the local video or enter the Youku video play connection to play it.

  4. When the video is being played, enter the client playing page and click the button.How does Youku client open local video/open online video? , you can choose to open the local video file or open the online URL of Youku website to play.

Tips:

  Youku PC client can only play. kux and. flv local files downloaded by Youku client.

  Youku PC client can only open the video playback URL connection of Youku website.

  YoukuNamely youku. com. Youku is the leading video sharing website in China and the first brand in the online video industry in China. Founded by Gu Yongqiang on June 21st, 2006, Youku.com takes "the fastest is king" as its product concept, pays attention to the user experience, and constantly improves its service strategy. Its outstanding product features of "quick play, quick release and quick search" fully meet the growing diversified interactive needs of users, making it a leading force in China video websites.

  Youku.com has now become a camp where Internet photographers gather. On December 8, 2010, US Eastern Time, Youku was successfully listed on the new york Stock Exchange. On March 12, 2012, Youku andpotatoCo., Ltd. jointly announced that the two parties signed the final agreement on March 11th, and Youku and Tudou will merge by 100% share exchange. The new company was named Youku Tudou Co., Ltd..

Youku

  Youku adheres to the high-end and atmospheric brand route, and the longest advertising time dominates the whole Internet, which is deeply criticized by netizens. Guided by the "joint plan", Youku has joined hands with many partners to integrate resources and expand content, fully drawing on the experience of cross-platform media operation, and using the unique attributes of video media to create a "network-platform interaction" communication mode, constantly responding to the demands of the industry and netizens, and promoting the streaming process of online video industry owners. In addition, Youku is the only commercial website that has obtained double certificates of broadcasting and television, and has become a legal platform for the distribution, dissemination and marketing of genuine film and television programs.

  Youku has been practicing the mission of "three networks in one", and now it has covered the Internet, TV,moveThe three terminals, which have three forms of content: film and television, variety show and information, run through the three links of video content production, broadcasting and distribution, and become the real Internet TV media, affecting the pattern of the video industry and the big pattern of the all-media era.

What is Youku?

  Based on video sharing, Youku develops a successful application model of triple play, providing users with the highest quality service for browsing, searching, creating and sharing videos. Youku is a comprehensive interpretation of Gu Yongqiang’s concept of "micro-video". Regarding the origin of the screen name of "Youku", Gu Yongqiang said: "Excellence represents the quality of service, and Youku advocates a quality video culture, so that the quality content can surface and the user value can be fully displayed; Cool, representing the user experience, the first time to taste the unique video buffet, to meet the enthusiasm of everyone to participate and the expression of personalized lifestyle. " In Youku, you can browse, upload, search and share colorful micro-video content fastest and most conveniently.

Heilongjiang announced the city scope of land border ports, and it is necessary to hold a negative nucleic acid certificate within 48 hours before leaving.

  According to the website of Heilongjiang provincial government on 24th, suifenhe city, Dongning City, Fuyuan City, Tongjiang City, Mishan City, Raohe County, Jiayin County, Luobei County, Aihui District and Xunke County are now declared as land border port cities according to the requirements of the State Council’s joint prevention and control mechanism for novel coronavirus epidemic.

  In order to effectively control the risk of epidemic spread, from the date of announcement to March 15, 2022, you must have a negative nucleic acid test certificate within 48 hours when you leave the above port cities. Please ask the relevant personnel to seriously abide by the requirements of epidemic prevention and control, and cooperate with relevant departments and units to check the nucleic acid test certificate. If the epidemic prevention and control obligations are not fulfilled and the spread of infectious diseases is caused, they will bear corresponding legal responsibilities.

  Hulin City, Sunwu County, Huma County and Mohe City will strengthen the implementation of epidemic prevention and control measures according to the above-mentioned land border port cities.

Guangxi CDC issued a health reminder in September to prevent diseases such as dengue fever and hand, foot and mouth disease.

Original title: Guangxi CDC issued a health reminder in September to prevent diseases such as dengue fever and hand, foot and mouth disease.

    Pay attention to personal hygiene, do not pick or eat wild mushrooms.

    On September 5th, Guangxi CDC issued the September Health Reminder, telling the public to take precautions against dengue fever, monkeypox, hand-foot-mouth disease, other infectious diarrhea caused by norovirus, acute hemorrhagic conjunctivitis, imported malaria, novel coronavirus infection and other infectious diseases, as well as food poisoning. The doctor reminded us to pay attention to personal hygiene and do a good job in self-health monitoring.

   ● Dengue fever removes stagnant water to prevent Aedes mosquitoes from breeding.

    Song Xiaoling, a member of the expert group on medical treatment of infectious diseases in Nanning and director of pediatrics of the Fourth Municipal Hospital, said that dengue fever is an acute insect-borne infectious disease and a Class B infectious disease stipulated by China’s Infectious Diseases Law. There are two epidemic situations of dengue fever: local epidemic and imported epidemic.

    At present, the main vector of dengue fever is Aedes albopictus. The virus is transmitted to humans through mosquito bites. Mosquitoes usually get infected when they suck the blood of infected people. Infected mosquitoes can spread the virus all their lives, and a few can pass the virus to their offspring through eggs.

    "The incubation period of dengue fever is generally 3 to 14 days, and most of them are 5 to 8 days. Patients and recessive infected people are the main sources of infection, and patients are contagious from 1 day before onset to 5 days after onset. " Song Xiaoling said that when a sudden high fever rises to 39~40℃ within a day or two, accompanied by symptoms such as measles and hemorrhagic rash, it is necessary to consider whether you are infected with dengue fever and go to the hospital in time.

    The best way to prevent dengue fever is to remove stagnant water, prevent Aedes mosquitoes from breeding and avoid being bitten by mosquitoes.

    Song Xiaoling suggested that citizens should wear light-colored long-sleeved clothes and trousers when going out in the environment with deep grass and dense forests, and apply mosquito repellent or mosquito repellent drugs on exposed skin and clothes as much as possible; Try to avoid staying in the shade, grass and other outdoor darkness for a long time during the frequent occurrence of "spotted mosquitoes". At the same time, do a good job in cleaning the family environment.

   ● Hand-foot-mouth disease mostly occurs in infants under 5 years old.

    Hand, foot and mouth disease is an infectious disease caused by enterovirus, which mostly occurs in infants under 5 years old. It is mainly transmitted through fecal-oral route, followed by respiratory droplets.

    Nanning Maternal and Child Health Hospital is a designated treatment institution for severe hand, foot and mouth disease in Nanning. Based on the detection of coxsackie virus A16 RNA, enterovirus universal RNA and other commonly used viral nucleic acids, the hospital introduced a rapid detection of EV71-lgM antibody against hand, foot and mouth disease, and the results were obtained within one hour.

    Yan Yunying, director of pediatrics at Nanning Maternal and Child Health Hospital, said that according to clinical monitoring data, the number of cases of hand, foot and mouth disease has increased recently. There are more than 20 types of enteroviruses that cause hand, foot and mouth disease. Coxsackievirus A, Coxsackievirus A, Coxsackievirus B and Coxsackievirus 71 are the common pathogens of hand, foot and mouth disease, among which Coxsackievirus A16 (CoxA16) and Coxsackievirus 71 (EV71) are the most common.

    Doctors reminded that vaccination with EV71 vaccine can prevent hand, foot and mouth disease caused by EV71 virus and reduce the occurrence of severe cases and deaths.

    Pay attention to hand hygiene, especially wash your hands before touching your mouth and nose, before and after meals, after changing diapers or handling items contaminated by feces.

    Pay attention to environmental hygiene. Open the window regularly every day for ventilation, do a good job of cleaning and disinfection, clean the home environment regularly, especially clean and disinfect children’s tableware, clothes, toys and other items, and wipe and disinfect the surfaces of objects such as the floor, desktop, door handle and bed fence at home.

    Try to avoid taking children to places where people gather and the air circulation is poor.

    Parents should pay more attention to the health status of young children, and go to the medical institution for treatment in time in case of fever, rash (especially perianal rash) or oral herpes.

   ● Monkeypox is mainly transmitted through men who have sex with men.

    Monkeypox is a zoonotic disease caused by monkeypox virus infection, and people are generally susceptible. It is mainly spread through close contact with monkeypox cases, and articles contaminated with virus may also be infected with the virus.

    The main clinical manifestations are fever, rash and lymphadenopathy. Most cases have mild clinical symptoms, and the death cases are mainly people with low immunity such as untreated HIV-infected people.

    Since May 2022, the monkeypox epidemic has spread to many countries. Since June 2023, many provinces in China have reported the epidemic situation of monkeypox, which is mainly spread by men who have sex with men. Men who have sex with men are the key groups infected with monkeypox. Recently, some areas in Guangxi have reported the epidemic situation of monkeypox among men who have sex with men.

    Disease control experts reminded that key populations should strengthen self-protection, reduce high-risk behaviors, avoid close contact with people with suspected monkeypox symptoms, and do not share clothes, bedding and other daily necessities of suspected cases. Self-health monitoring should be done if there is a history of suspicious contact; Entry-exit personnel should pay attention to the information of monkeypox epidemic situation in destination countries and regions, and do not contact people with monkeypox-like symptoms, rodents, primates and other animals.

   ● Imported malaria Try to wear long trousers outdoors.

    Malaria is a blood parasitic disease caused by the bite of Anopheles mosquitoes, which is also called "cold fever", "malaria" and "malaria". Africa and Southeast Asia are highly endemic areas of malaria.

    Disease control experts remind you to do personal protection, especially outdoors, and try to wear protective clothes, such as long sleeves and trousers. Exposed skin can be coated with mosquito repellent. Pay attention to environmental sanitation, remove garbage, weeds, fill sewage pits, and do a good job in mosquito control.

    Before going abroad, you should know the epidemic situation of malaria and other diseases in the destination and make personal protection preparations; After returning from Africa, Central and South America and Southeast Asian countries, if you have symptoms such as chills, fever, sweating and fatigue, you should go to a regular hospital as soon as possible and take the initiative to inform you of your living history.

   Norovirus does not eat half-baked sea (water) products.

    Norovirus is an acute intestinal infectious disease, which has the characteristics of acute onset, rapid spread and wide coverage. It is mainly spread through food and water contaminated by patients’ feces, or through close contact. The epidemic situation mostly occurs in schools, kindergartens, nursing homes and other places where people gather. The most common symptoms are diarrhea, vomiting and nausea.

    Disease control experts remind people to pay attention to personal hygiene and wash their hands frequently, especially before and after meals and before food processing.

    Food should be fully heated before eating, tableware should be disinfected regularly, and eating out should try not to eat half-baked sea (water) products.

    After the ground or objects are polluted by patients’ vomit or excrement, the pollutants should be cleaned and disinfected immediately under the premise of personal protection.

   ● Don’t rub your eyes with dirty hands for acute hemorrhagic conjunctivitis.

    Acute hemorrhagic conjunctivitis, commonly known as "pink eye", is a highly contagious acute eye disease caused by enterovirus. Through contact, eye-hand-eye is the main route of transmission. The clinical manifestations are tingling, gritty foreign body sensation, burning sensation, photophobia, tears, eyelid edema and high congestion of eyelid and bulbar conjunctiva.

    Ophthalmologists remind us to pay attention to personal hand hygiene and eye hygiene, wash our hands often with soap, try not to rub our eyes with dirty hands, and develop the hygienic habit of dividing towels and basins.

    Strengthen the sanitary management and supervision of swimming pools, baths, barber shops and hotels.

    If there are patients with infectious acute conjunctivitis at home, their daily necessities such as towels and washbasins should be disinfected. Do not share towels, bath towels, eye cosmetics or personal eye care products.

   ● novel coronavirus should still adhere to personal protection when it infects the public.

    At present, the overall prevalence of infection in novel coronavirus is at a low level. The public should still adhere to personal protection and be the first person responsible for their own health.

    Please complete the vaccination as soon as possible for those who meet the requirements but have not been vaccinated, have not been vaccinated in the whole process and have not been vaccinated, especially for the elderly over 60 years old.

    Wear a mask scientifically and regularly, wash your hands frequently, often ventilate, cover your mouth and nose when coughing or sneezing, and try to avoid contact with fever personnel.

    Eat a healthy diet, quit smoking and limit alcohol, work and rest regularly, ensure adequate sleep, and exercise moderately according to your own situation.

    The elderly, children, key people with chronic diseases and pregnant women should stay away from people with fever and cough symptoms, do a good job in health monitoring, and seek medical advice in time if they have fever and other discomfort; Wear masks during the whole process of medical treatment, and try to avoid taking public transport.

   ● Prevent food poisoning and do not pick edible wild mushrooms.

    Continuous high temperature creates suitable conditions for bacterial proliferation, food is easy to rot and deteriorate, and the risk of microbial food poisoning increases. In addition, September is still the peak season for the growth of all kinds of wild mushrooms in Guangxi, and with abundant rain, poisonous mushroom poisoning incidents are prone to occur.

    Deng Shangqin, a health science expert in Guangxi and director of the dog injury clinic of the Fourth Hospital of the City, reminded not to deliberately purchase fresh rare mushrooms or mushrooms that are unknown or claimed to be new products. Parents should remind their children not to pick when they take them to play in the grass and Woods, in case the children grab something to eat or eat their hands without washing their hands after picking, resulting in poisoning due to mushroom poison on their hands. "Some poisonous mushrooms are very toxic. After picking, they are unintentionally crushed, and the oozing poisonous juice touches the hands. A few milligrams of mushroom toxin may lead to acute poisoning and even death." (Reporter Ye Wei)

Give 100 thousand! Can undergraduates do scientific research well?

  At the beginning of August, Zhang Chenyang, a senior student in Tsinghua University, received a notice from the college that he would participate in the selection of the Young Students’ Basic Research Project (hereinafter referred to as the Young Students’ Project) of the Natural Science Foundation of China on August 22, and he could choose any topic as long as the basic research related to natural science was concerned, and the project cycle was one or two years.

  As the most important funding channel for basic research in China, the National Natural Science Foundation of China (hereinafter referred to as NSFC) brought undergraduates into its talent funding system for the first time, which attracted attention. In late August, the National Natural Science Foundation of China held the first evaluation meeting of young students’ projects in Beijing and Hefei. As a pilot, outstanding undergraduates from eight universities including Peking University, Tsinghua University and China University of Science and Technology (hereinafter referred to as China University of Science and Technology) were recommended to participate in the interview.

  China News Weekly learned that up to now, the evaluation and selection of this project has been completed, and those who pass the selection can get a research fund of 100,000 yuan. According to official website, the Intelligent Research Laboratory of the Chinese University of Science and Technology, an undergraduate student in the laboratory has received relevant funding. When the project was first announced, it once aroused doubts in the scientific community: Do undergraduates have enough ability to do scientific research?

  Who can get funding?

  Zhang Chenyang is an undergraduate of the first "Strong Foundation Program" in Tsinghua University, which was launched in 2020 to select students with excellent comprehensive quality or top-notch basic research. Shortly after entering school, Zhang Chenyang, with the encouragement of his tutor, tried to carry out a scientific research project in the field of ancient building restoration that he was interested in. He spent half a year researching and experimenting, and as the first author, published the research results of this project in the domestic core journal Journal of Geotechnical Engineering. This experience opened a new world for Zhang Chenyang. "This result made me very satisfied, and I began to feel that the process of doing scientific research and solving problems was very interesting, which was very different from learning in class."

  During his school years, he participated in many projects to support undergraduate scientific research, such as Tsinghua University’s "Academic Research Promotion Plan for College Students" and "Spark Plan", and the national training plan for college students’ innovation and entrepreneurship. In July, 2021, after the extreme rainstorm in Zhengzhou, Zhang Chenyang decided to turn to the research on flood forecasting and early warning. This is also the theme of Zhang Chenyang’s application in this young student project.

  Over the years, the Natural Science Foundation of China has built a funding chain for talent projects, including "excellent youth", "outstanding youth" and innovative research groups, but the funding targets are all scholars engaged in scientific research. Putting the talent funding port ahead is a new reform of the Natural Science Foundation of China this year.

  In May this year, the NSFC had a preliminary idea. In June, Dou Xiankang, Party Secretary and Director of the NSFC, led a team to Tsinghua, Peking University and other universities for investigation. In an exclusive interview with China Newsweek at the beginning of July, Dou Xiankang mentioned that during their investigation, they noticed that there are indeed some undergraduates who have spare capacity in learning and have interest and talent in scientific research. He has also seen some students who have completed their four-year courses in just one and a half years, thus having more time to do research. Judging from the law of talent growth, early discovery and targeted training of outstanding young talents will help them stand out as soon as possible and make great progress in the future, and also provide "flowing water" for building a high-quality basic research talent team.

  The speed of the project is beyond many people’s expectations. In July, the project for young students was formally established, and in August, the Natural Science Foundation of China organized a meeting review. "We completed all the evaluation work before the end of August, in order to complete the project establishment and funding in September, so that students can start the project at the beginning of the new semester and invest in the project research." Dou Xiankang said.

  Dou Xiankang said that at present, the project is still in the pilot stage, and the Natural Science Foundation of China hopes that the scope will be smaller, so the model of "recommendation+evaluation" will be adopted, and all students participating in the evaluation will be selected by universities according to relevant requirements. At the same time, however, in order to provide excellent students with opportunities for training and support, there is no quota limit for judging, and applicants with excellent performance can get financial aid. On August 22nd, Zhang Chenyang went to the office building of NSFC to participate in the selection. He noticed that there were about thirty or forty students from Tsinghua and Peking University.

  The selection of undergraduate programs is different from the projects of "Jieqing" and "Youqing" of the Natural Science Foundation of China. According to reports, in the evaluation of young students’ projects, students should show their projects within the specified 8 minutes and answer experts’ questions within the remaining 17 minutes. Dou Xiankang once mentioned to China Newsweek that there is no need for college students to present scientific research results like "Jie Qing", and the questions raised by some students may not be mature, but the judges can generally see whether the students have a solid scientific foundation and enthusiasm for science — — This is an essential quality for scientific research.

  Pan Xin, Dean of School of Aviation Science and Engineering, Beihang University, is one of the experts in the evaluation of young students’ projects. He condensed the criteria for judging students into one: whether students have the ability to ask questions. In the question-and-answer session, he will discuss with the students why he did this topic. The question is raised by himself or his tutor. "Perhaps most students have jointly raised questions after discussion with their tutors. After all, they are still young and have to attend classes. It is not easy to do this in a short time in a brand-new field."

  Pan Yi told China News Weekly that most of the students who participated in the evaluation were sophomores and juniors. He remembers that some students studied urban planning and management, used new tools to do big data analysis of regional economic heat, and evaluated regional economic vitality. "This is a social science topic, but it impressed me deeply. In the process of students’ migration from the field of partial management to the direction of mathematics and physics, new problems in cross-cutting fields were excavated." There is also a student who studies the stability of gravitational wave antenna device, hoping to solve the problems in the existing technology by designing new engineering and software.

  In addition, unlike the previous project review, the Natural Science Foundation of China suggested that the judges discuss with the students by means of communication rather than defense, "to inspire and guide them as much as possible and stimulate their interest in scientific research". When Pan Yi communicates with these children, he can feel that they all have a good theoretical foundation, but they also need more and wider academic exchange opportunities.

  When Zhang Chenyang applied for related scientific research projects before, he was mostly asked about the professional knowledge of the project, and the tutors in the school mostly communicated with him about the details of the plan. At the review site, seven or eight experts from the audience raised about 10 questions, including basic knowledge, research experience, scientific research plan, etc., and some teachers gave him suggestions on research ideas. "I want to study the early warning of mountain torrents in North China, and then spread the experience to the whole country. A teacher at the scene suggested that I can do experiments nationwide first, and then sum up good methods. This and my research are two kinds of ideas, which can give me some inspiration. "

  In addition, we need to pay attention to how to select students who are really interested in scientific research, so that the young student project will not become the "hat" of undergraduates. According to Mu Rongping, a researcher at the Institute of Science and Technology Strategy Consulting of China Academy of Sciences, some talent funding projects have become "hats", which has nothing to do with the funding itself. The problem is that subsequent employers regard these funding as a precondition for talent admission or evaluation. Funding outstanding undergraduates to do scientific research may not be a prerequisite for sending graduate students, which may be helpful to the selection of talents for young students’ programs.

  Can undergraduates do scientific research well?

  In the evaluation team that Pan Yi participated in, the projects declared by 11 students were very difficult, "it is difficult to make a complete solution in a short time", but Pan Yi did not expect these students to publish several papers or patents two years later, or to push the research problems to a new height. In his view, the real value of the young student project lies in that students can receive the training of scientific research paradigm and be more firmly involved in scientific research in the future. Mu Rongping pointed out to China Newsweek that the establishment of this project by the Natural Science Foundation is also in line with the laws of scientific research. Students need to participate in basic research, attend more academic conferences, communicate with outstanding peers at close range, and improve their thinking ability in solving scientific problems.

  According to reports, on August 21st, the day before the evaluation of young students’ projects, NSFC invited Pan Jianwei, an academician of China Academy of Sciences, Luo Yi, executive director of the Department of Chemistry and Physics of Chinese University of Science and Technology, and other scientists to give academic reports to the undergraduates who participated in the evaluation. Dou Xiankang said, "In the future, we will provide them with more opportunities to participate in comprehensive high-end scientists’ forums, hoping to inspire and guide them to embark on the road of scientific research by letting top scholars at home and abroad communicate face to face with outstanding undergraduates, making reports, talking about experiences and feelings."

  Mu Rongping told China Newsweek that, according to the laws of scientific research, different disciplines are different, and many scientists at home and abroad have made outstanding achievements at a young age in basic theoretical disciplines such as mathematics and physics. At present, the young students’ program is still in the pilot stage, with a small number of students selected and a low amount of funding, which may not be as much as a large project of the Natural Science Foundation of China. It is a good attempt to select students who are really interested in scientific research, and the outside world can give more tolerance.

  Pan Xin has more than ten years of teaching experience, and is also responsible for the teaching reform planning and scientific research development of the college. In his view, the young student program is a "flag" and signal, that is, the state attaches importance to the coordinated development of education, science and technology, and talents, which can guide more university administrators to think about talent training at the undergraduate level.

  Pan Yi pointed out to China Newsweek that most of the courses at the undergraduate and postgraduate levels in domestic universities are imparting known knowledge. There are fixed class hours in one semester, and what to talk about in each class will be planned in advance, eventually teaching students a set of systematic knowledge. Only when students really enter a research topic can they begin to transition to exploring the unknown. He hopes that this process can be advanced.

  As early as 2005, the famous "Qian Xuesen’s question" was put forward. Today, how to cultivate top-notch innovative talents is still a common challenge for China University. Pan Yi noticed that some undergraduates, even postgraduates, lack scientific research training, and it is difficult to write a paper that people can understand. In his view, China’s basic education, undergraduate courses and practical equipment in some universities are not bad, but in the postgraduate stage, there will be a clear gap between China and top foreign universities. In top foreign universities, most natural science courses are required to write papers or reports at the end of the class. Students need to think, investigate and explore the unknown on the basis of the classroom knowledge system, but most courses in domestic universities still test the known content.

  Mu Rongping believes that what is more important behind the young students’ project is how colleges and universities can reverse the learning and thinking habits of undergraduates, and turn from memorizing answers to discovering and exploring problems. "The key to real scientific research is to see who can find the real problems".

  Lu Xiaodong, a researcher at Peking University Institute of Education, has been paying attention to undergraduate research for many years. In his view, NSFC’s funding for undergraduates is not new, but there is a new funding channel. Over the past 20 years, many universities in China have been supporting undergraduates who have the ability to learn to participate in scientific research. The traditional impression that "doctor is the entry stage of scientific research" is actually a cognitive misunderstanding.

  Take Peking University as an example. In 1998, Li Zhengdao set up a "political fund" to introduce the scientific research model of American research universities into China. Subsequently, Peking University established a set of management system with "research courses" as the core, and incorporated undergraduate scientific research into the regular curriculum. Relevant subsidies included "political fund", "president fund" and "Mao Yugang fund". According to the "research course" of Peking University, the applicants should be sophomores, and their GPA should rank in the top 30% of the college. At the same time, the standardized management of the course requires students to ensure that they invest enough time, and there are requirements for the mid-term and completion of the project.

  Pan Wei introduced that since 2021, Beihang University has conducted pilot research classes for sophomores and juniors. Each pilot college will open a research class as an elective course, accounting for 2 credits, and requires key laboratories at or above the provincial level to invest certain experimental conditions to support students. Pan Yi mentioned that compared with the traditional classroom, the scientific research classroom is open, and students may be faced with the most cutting-edge science and technology in a certain field. They can do experiments, research or theoretical formula derivation. There is no standard answer to this process. The most important thing for students is to learn scientific research paradigm, cultivate the ability of literature research, independently design operable experiments and write experimental reports.

  "We have been piloting for 3 years, and about 90% of the undergraduates of Beihang University have taken scientific research classes. I obviously feel that after the preliminary training, the level of graduation design has been significantly improved." Pan Yi told China Newsweek. Lu Xiaodong once met some undergraduates who quit halfway because of lack of interest when doing scientific research projects. There are also some students who have participated in short-term laboratory projects in different disciplines. Many teachers have found that these students are seriously involved in each project, and they gradually clarify the future research direction in the process, even if they do not produce visible research results, they are also very valuable.

  Compared with China, foreign top research universities began to encourage undergraduates to do research earlier. As early as 2000, Lu Xiaodong went to the United States to inspect the management of first-class universities, focusing on undergraduate education at the University of California, Berkeley. As a research university, Berkeley attaches great importance to undergraduate scientific research, and even regards it as an important part of undergraduate education. Since the 1990s, the university has set up special funds to support undergraduates to do scientific research. In 1997, it set up an undergraduate research office to organize and serve students’ research. Besides providing some information about project application, it will also help students understand what research is, how to write project applications and draw up reports through lectures. In addition, Harvard University, Massachusetts Institute of Technology, California Institute of Technology and many other American research universities have set up relevant institutions and projects to support undergraduates to do scientific research.

  The undergraduate stage is a critical period for the cultivation of academic aspirations. Lu Xiaodong noticed that many alumni of Peking University who have made their mark in academia or returned to school as teachers have participated in research courses at the undergraduate level if they look at their resumes. In 2023, Zhang Cheng, a professor at Fudan University School of Management, and others published an article "The Impact of Undergraduate Research Projects on Personal Research Career Development — — In a retrospective cohort study, the research career development of undergraduate students and graduates of Fudan University from 2000 to 2017 was investigated, and the final sample included 576 data. It is found that compared with students who have not participated in scientific research projects, the probability of undergraduates who have participated in related projects graduating from doctoral programs has increased by 14.1%, and the probability of choosing scientific research positions in formal jobs has also increased by 17.2%.

  The article points out that the important reason is that early scientific research training promotes students’ understanding of scientific research and cultivates students’ self-confidence in this field. Zhang Cheng and others believe that the key is not simply to let students take part in teachers’ topics or simply to pursue the publication of articles, but how teachers guide students to complete scientific research tasks, achieve goals and constantly build confidence in this process.

  Relevant research points out that domestic undergraduate research projects have been carried out for many years, but the overall start is late, the coverage is narrow, the implementation effect of different universities is uneven, and relevant policies still need to be improved. Lu Xiaodong observed that in the past years, some university administrators have also visited Peking University to investigate their experience. In his view, the most important thing is that school administrators and teachers should first change the concept that gradual learning at the undergraduate level and problem-centered learning triggered by undergraduate research do not conflict, but will promote each other. To support undergraduates in scientific research, colleges and universities should first straighten out this problem. Secondly, relevant experts believe that the integration of undergraduate scientific research into the formal curriculum will help reduce the conflict between students’ participation in scientific research and course learning.

  In addition, experts say that domestic universities need to invest more resources in undergraduate research. In China, except for some top universities, most of the undergraduate research work is assigned to the Academic Affairs Office. The relevant teachers lack enough energy and time to organize undergraduate research, and some teachers lack understanding of undergraduate research training, so it is difficult to undertake detailed guidance. At the University of California, Berkeley, in order to support teachers to participate in students’ scientific research, teachers will receive project assistance and a small grant of $ 300~600 to partially pay for students’ research-related expenses.

  How to motivate teachers to actively participate is very important. In Lu Xiaodong’s view, taking undergraduates to do research really requires teachers to invest more energy. Some colleges and universities can give priority to selecting some willing excellent teachers. Teachers should also think clearly about the value and significance of this matter. Undergraduate scientific research courses can play a real role in the process of cultivating top-notch innovative talents, but it is not achieved overnight.

  (Zhang Chenyang is a pseudonym in the text)

  Published in China Newsweek magazine, No.1110, September 25th, 2023.

  Magazine title: Natural Science Foundation of China subsidizes undergraduates for the first time.

Four routines of epidemic rumors

This article comes fromWechat WeChat official account: DT Finance (ID: dtcaijing)Author: Zhang Beidi, data: Zhong Dai, editor: Amy, Xiao Tang, design: Zhao Yun

The Lunar New Year in 2020 not only tests the determination of young people to save themselves at home, but also tests their ability to persuade their relatives to wear masks with emotion and reason.

But this is only the initial test, and the advanced is how to deal with rumors.

Family WeChat group, the source of rumors, and the high incidence area of IQ tax.When relatives warn their relatives and friends here in the name of "forwarding to save the whole life" and "expert emergency reminder", do you often clench your fist but there is nothing you can do?

What’s even more troubling is that many rumors look so similar that you can’t recognize them and even forward them to your circle of friends.

So is Ya Wen.

Yawen is a teacher in Changsha. During the Spring Festival at home, she not only prepares lessons for students, but also dispels rumors for her parents. Through the WeChat group, two dietotherapy fans kept forwarding "expert recommendation! These foods can resist Covid-19! " Class articles, even bought 10 Jin of Houttuynia cordata "said to be useful" to boil water to drink. This made Yawen laugh and cry.

In the face of these revelations from "insiders" and various WeChat screenshots, Yawen is also somewhat powerless. The huge amount of information makes it difficult for her to identify some specious rumors in an instant.

In order to let you see the rumors in this epidemic more comprehensively, we have collected more than 1,000 rumors since the outbreak of COVID-19 on various platforms. This is not only a routine to let you see through rumors, but also to provide you with some tips to prevent rumors in the current information surplus.

1. What are the characteristics of popular rumors during the epidemic?

Some rumors during the epidemic are "false at a glance" for young people, and it is difficult to identify them. For example, drinking high-alcohol anti-virus, smoking anti-virus, drinking urine anti-virus. Of course, these rumors were not only discovered by most netizens in an instant, but also became Prozac in a long holiday.

But there is another kind of rumor, which at first glance makes some sense, so it is not so easy to distinguish it.

We collected and sorted out the suspected rumors collected and summarized by Lilac Garden and Sina’s official @ Catch Rumors @ during the COVID-19 epidemic, and divided them into popular science rumors and event rumors. Let me make a general comb for you first.

So far, among the popular science rumors compiled by Lilac Garden,Most rumors are related to the type of virus, the route of transmission, effective drugs and masks.

The latest popular rumor is "Covid-19 belongs to SARS virus" which was born on February 9th. But last night, you already knew through hot search and official response-this was actually a "slip of the tongue".

After the "slip of the tongue", the popular rumor that has been confirmed as a rumor is "Can the paper towel in the mask be used repeatedly?" And "Zhong Nanshan team prescribed Chinese herbal tea?" Their answers are all in the negative. So stillTry to use a mask at one time, don’t trust the cure, and go out less is the first stunt of safety.

If you look around, you will find that,The birth and spread of this part of popular science rumors is mainly due to "interlacing like a mountain."We ordinary people have no ability to distinguish information involving professional knowledge in a certain field, and we can only trust authoritative people. Therefore, we find that the spread of these event rumors is often attached to an important name.

Among the most topical rumors published by @ Catch a Ballad, the top three are "Academician Zhong Nanshan infected COVID-19", "Academician Zhong Nanshan suggested gargling with salt water to prevent virus" and "Bai Yansong invited Zhong Nanshan to be a guest in News 1+1 on the evening of 26th". I believe that you have heard all these rumors, and without exception, you tied yourself to the name "Zhong Nanshan". They seem to be well-organized, and they are all rumors without exception.

In this way, you can see such rumors that are difficult for us to distinguish.In fact, it is to use the blind spot of knowledge and the celebrity effect to make rumors.Some rumors will combine the two, which really looks like that.

2. Typical routines of rumors

In order to better identify the routine of rumors, we have sorted out more than 1,000 rumors from today’s headline rumor collection, WeChat WeChat official account rumor collection, Sina rumor collection, and Weibo account @ Weibo rumor collection, and made a careful analysis.

The first thing we studied was, in this epidemic, whichkeywordIt has become the first choice for rumor makers. As you can see,"Hospital", "mask" and "WeChat group" are the favorites of rumor makers, and place names such as Hubei, Shanghai, Wenzhou and Beijing are also popular. Of course, there is also the "Zhong Nanshan" mentioned earlier in the rumor-prone area.

After reviewing the rumors about masks, we found that,Rumors about masks are also divided into several factions.. One kind of rumor is that the mask can be used after being blown by a hair dryer or disinfected with alcohol; One kind is that the masks purchased by foreign countries have been delayed to arrive because they have been requisitioned by the customs; There are also rumors that some car trunks come standard with an N95 mask … In short, as the number one scarce product in this holiday, rumors about masks have never stopped.

"WeChat group" ranks third among the key words of rumors, because "WeChat group" is almost the common beginning of rumors:"Someone in a WeChat group said …".

If rumors are classified according to their contents, these sample rumors can be divided into four routines:City closure, medical prevention and control, and folk anti-epidemic methods are related to Wuhan.

Since Wuhan temporarily closed the passage from the Han Dynasty, rumors about the closure of the city have also begun to splash. Among the keywords, you can see the names of Beijing, Shanghai, Chengdu and Nanjing. There are such means as "stopping traffic", "blocking roads" and "prevention and control", and there are also some figures.

To sum up, most of the rumors of city closures have a similar one.templateBecause of the demand for prevention and control, the road in X city was closed and stopped from X day.Because of the painful experience during SARS, Beijing in the epidemic is also the most common city among the rumors of city closure.

Rumors of medical prevention and control have also risen with the epidemic.

Since the outbreak of the epidemic, news about the shortage of medical resources has been broadcast on TV, and various videos recorded in hospitals have been madly transmitted in the WeChat group, which has aroused public concern and concern about medical prevention and control in various places. In this context, many people believe the rumors such as "the emergency treatment in a certain hospital stopped", "the doctors and nurses in a certain hospital were infected with COVID-19" and "the confirmed cases in COVID-19 fled from the hospital".

In the rumors of folk epidemic prevention, you can strongly perceive the anxiety of ordinary people.

In addition to the N ways we mentioned earlier about the use of masks, this accounts for the bulk of the rumors of anti-epidemic among the people. In the rumors, you can also see such means as "garlic", "Shuanghuanglian" and "hot bath", as well as effect-oriented words such as "prevention" and "treatment".

There is also a large category of rumors, mainly around Wuhan.On the one hand, there are many rumors about materials and medical assistance in Wuhan; On the other hand, there are many rumors about Wuhan people moving to various provinces and cities and even abroad.

Due to the recent inaction and chaos of the Red Cross Society in Hubei and Wuhan,Wuhan and the Red Cross.Related news received the most attention, which also attracted the most rumor makers, resulting in rumors such as "Wuhan Red Cross charged 6%~8% of the handling fee to Shanghai medical team" and "Wuhan Red Cross sold vegetables donated by Shouguang".

On the other hand,The data of 5 million people flowing out before the closure of Wuhan triggered a public opinion earthquake.Immediately after that, there were similar rumors, such as "novel coronavirus, a family of three in Wuhan, was diagnosed during a Disney visit", "116 Wuhan tourists were denied entry and repatriated to Hangzhou" and "a Wuhan woman ended the French strike, and the French went to grab masks".

The most amazing thing is that one isThe license plate number of "Zhejiang BL0535". In the versions of rumors in various places, the owner of this license plate number has been diagnosed as COVID-19, whose main task is to wander around the country as far as Tibet. After verification by the public security organs, there is no vehicle registration information under this license plate number.

With the change of time, the subject of rumors is also changing.

Just like the change of epidemic situation, the number and subject of rumors are changing with time.

In terms of quantity, although the number of rumors declined in early February, the overall trend is still increasing. In the six time nodes before January 20th, @ Weibo refuted 1.2 rumors every day on average. However, from January 21st, the number of rumors began to increase with the news of "people-to-people", and suddenly broke out on January 25th.

arrivedJanuary 29The number of rumors reached the first high point, 48. After that, the number of rumors dropped slightly. But inFebruary 7th.The number of rumors reached a new high, reaching 58.

By comparing the data with the news background, we find that:There are usually major events around the nodes with high rumors.

For example, on January 20 thZhong Nanshan announced that the virus was "human-to-human"; After the closure of Wuhan on January 23, it came out.Other cities outside Hubei followed suit and closed the city.Rumors that Zhong Nanshan was infected with the virus also occurred at this time.

On January 27,Low working efficiency of Wuhan Red Cross Society.It not only produced a large-scale spontaneous supervision by netizens, but also produced a series of exaggerated events.

By early February,Should I rework it?It has caused widespread discussion, and urban disinfection has also triggered the birth of many rumors.

In various time periods, major or absurd events will attract a lot of attention.In the process of transmission, some information will be misinterpreted and misunderstood, so that while the real news is exposed, there are new rumors.

When a large number of rumors are produced and interfere with audio-visual, we can actually describe their spread process with a formula.American sociologists G·W· allport and L Postman once summed up a formula of rumor: rumor = importance * vagueness.

This means that if a rumor is important enough, plus ambiguity, it has sufficient conditions for rapid spread. Sometimes, rumors that do not have such conditions will become full of flavor after being increased, decreased and strengthened in the process of communication. So the rumors spread more and more outrageous.

Later, communication scholarsCrossAfter developing this formula, it is put forward that rumor =(of events)Importance x(of events)Fuzziness, public critical ability.Explain how powerful rumors are, which depends on both the transparency of real information and the judgment level of the audience.

Therefore, how far and far rumors can spread is not only testing the judgment ability of the audience, but also testing the efficiency and transparency of the authoritative department.

All kinds of rumors and false information will not only be of no help to the epidemic, but also increase the psychological burden of the masses, aggravate the panic of the society and undermine the confidence in comprehensively fighting the epidemic. Therefore, in this epidemic war, the battle about information and rumors is also very important.

In the matter of stopping rumors, we can try our best to be rational and use our knowledge and logical reasoning to prevent those false rumors from spreading more widely.

But we all know that ordinary people really don’t have the ability to distinguish information with professional knowledge barriers. At this time,More open and reliable information from authoritative organizations and professionals may be the effective way to fight rumors.At worst, the above-mentioned people and institutions can make fewer slips of the tongue and be more rigorous, which is a positive contribution to stopping the epidemic.

This article comes fromWechat WeChat official account: DT Finance (ID: dtcaijing)Author: Zhang Beidi, data: Zhong Dai, editor: Amy, Xiao Tang, design: Zhao Yun                  

Fatty liver is not a "patent" for fat people. "Keep your mouth shut and open your legs" can be prevented.

  editorial comment/note

  Fatty liver has become the second largest liver disease after viral hepatitis in China. According to the epidemiological survey in Jiangsu, Zhejiang and Shanghai, the incidence of fatty liver in the local area is 15% ~ 20%. According to the conservative estimate of the national incidence rate of 18%, the number of people with fatty liver in China is 234 million, with an average age of only 40 years, and more and more patients are around 30 years old. The average incidence of fatty liver in some occupational groups (white-collar workers, taxi drivers, professional managers, individual owners, government officials, senior intellectuals, etc.) is 25%; The incidence of fatty liver in obese people and patients with type 2 diabetes is 50%; The incidence of fatty liver in sub-health people who often suffer from insomnia, fatigue and gastrointestinal dysfunction reaches 60%.

  Experts pointed out that fatty liver is related to bad eating habits such as drinking, high-fat diet, convenience food, fried food and snacks. In addition, the fast pace of life of modern people and the reduction of exercise are also important reasons. Experts remind that although most patients with fatty liver usually have no bad feelings, they should pay attention to it to avoid falling into five common misunderstandings, and incorporate healthy diet management and reasonable exercise into their daily lives to prevent and control the occurrence and development of fatty liver and avoid fatty hepatitis and even cirrhosis.

  ■ Smell and sing

  Recently, when attending a class reunion, a group of middle-aged people mentioned the fact that many people were diagnosed with mild or moderate fatty liver every year, not only these working middle-aged people, but even young people in their twenties and thirties are constantly joining the ranks, which makes everyone confused. Is there something wrong with our daily life?

  At present, it is an indisputable fact that the incidence of fatty liver is getting higher and younger. According to the epidemiological survey in Jiangsu, Zhejiang and Shanghai, the local incidence of fatty liver is 15% ~ 20%. According to the conservative estimate of the national incidence of 18%, the number of people suffering from fatty liver in China is 234 million.

  If you don’t drink, eat meat or get fat, why can you get fatty liver?

  Hu Chengheng, chief physician of the First Affiliated Hospital of Sun Yat-sen University, Guangdong Province, pointed out that fatty liver has become the second largest liver disease after viral hepatitis in China. The average incidence of fatty liver in some occupational groups (white-collar workers, taxi drivers, professional managers, individual owners, government officials, senior intellectuals, etc.) is 25%; The incidence of fatty liver in obese people and patients with type 2 diabetes is 50%; The incidence of fatty liver in alcoholics and alcoholics was 58%. The incidence of fatty liver in sub-health people who often suffer from insomnia, fatigue and gastrointestinal dysfunction reaches 60%. In recent years, the age of people with fatty liver has been declining, the average age is only 40 years old, and there are more and more patients around 30 years old, and the fatty liver in men under 45 years old is obviously more than that in women.

  As we all know, fatty liver is equated with drinking and high-fat diet, but what puzzles many people is why they get into this disease when they obviously don’t drink and eat meat very much. Cai Haodong, chief physician of beijing ditan hospital affiliated to Capital Medical University, believes that not drinking alcohol can also lead to liver diseases, and the incidence of nonalcoholic fatty liver is 9% ~ 46%. Most of them are simple fatty liver, mostly asymptomatic, and there is no inflammatory change in the liver, so the liver function is normal and the condition is stable.

  Yuan Xiaoying, chief physician of the Department of Gastroenterology, Chongqing Ninth People’s Hospital, believes that fatty liver is first related to diet. Nowadays, people’s lives are getting richer and richer, and it is inevitable that they will touch alcohol and high-fat food in their diet. However, modern people like to stay up late and work overtime, and they have to add meals at night when they work overtime, which are often convenience foods, fried foods and snacks. These are all bad eating habits; In addition, modern people have a fast pace of life, do not have much time to go out for exercise, and the amount of exercise is reduced, which is also the reason why the onset age of fatty liver is getting younger and younger and the incidence rate is getting higher and higher.

  Because many people who have been diagnosed with fatty liver have no bad feelings, they don’t really care. Shi Lei, deputy chief physician of hepatobiliary surgery in Xi ‘an Hospital of Traditional Chinese Medicine, reminded that doctors advocate early detection, early diagnosis and early treatment of fatty liver, especially steatohepatitis, which is not a simple fatty liver, but accompanied by inflammatory activities of the liver, and the hardness of the liver is also increasing. If not actively treated, fatty liver can also develop into cirrhosis, causing adverse consequences.

  Fatty liver is a common "five misunderstandings". Have you been recruited?

  Zhao Gan, a nutritionist at Beijing You ‘an Hospital affiliated to Capital Medical University, reminds you that even if you usually pay great attention to diet and health care, you may walk into the following five misunderstandings about fatty liver.

  Myth 1: Fatty liver is neither painful nor itchy, so you can leave it alone. Fatty liver is mainly divided into alcoholic fatty liver and nonalcoholic fatty liver, and mild fatty liver is easier to cure. However, if it develops to a serious stage, it may also lead to cirrhosis and liver cancer. Even with active treatment, the diseased liver is unlikely to return to normal.

  Myth 2: Only obese people get fatty liver, but thin people don’t. Fatty liver is not a "patent" for fat people. Some office workers are sedentary, resulting in excessive visceral fat and central obesity. Although their limbs are not fat and their trunks are not bloated, they are exposed as soon as they take off their clothes, and they are also prone to fatty liver.

  Myth 3: Fatty liver is eaten, and you only need to control your diet. To get fatty liver, you don’t just need to control your diet. You also need to quit smoking and drinking and strengthen exercise. Exercise is an important way to treat fatty liver, especially for obese friends. Generally, low-intensity aerobic exercise is more suitable, such as brisk walking, jogging and swimming. However, it should not be too intense. If the amount of exercise is too large, it may affect the liver function and aggravate the condition.

  Myth 4: Fatty liver patients eat more fruits, the better. Fresh fruit is rich in vitamins and minerals, and is rich in dietary fiber. Regular consumption is good for health, but the more you eat, the better. Because of the high sugar content of fruit, eating too much for a long time can lead to the increase of blood sugar and blood lipid, and even induce obesity. In addition, eating only fruits and vegetables instead of staple food will make patients with fatty liver more hungry, have disordered metabolism and unstable blood sugar level, which will aggravate fatty liver. Therefore, people with fatty liver should not eat more fruits, just in moderation, and should choose to eat between meals.

  Myth 5: Fast weight loss can reduce fatty liver. Some obese friends have fatty liver, and often take "hunger therapy" to lose weight quickly. In fact, losing weight too fast is often harmful. If it exceeds the metabolic capacity of the body, it will damage the liver function and aggravate the condition. For most patients, the reasonable weight loss goal is about 0.5 kg/week.

  With fatty liver, how to scientifically "shut up"?

  Zhao Yaping, a nutritionist at Beijing You ‘an Hospital affiliated to Capital Medical University, believes that in the occurrence of fatty liver, dietary behavior is the first to bear the brunt, and managing food intake has become the most important thing to prevent and control the occurrence and development of fatty liver.

  1. Dining system. 4-5 meals a day, 3 main meals and 1-2 extra meals. You can eat fruits and vegetables, yogurt and nuts during meals, so that you won’t be too hungry to eat too many calories at one time, and effectively control your appetite and food intake.

  2. Slow down the meal. Eating slowly can reduce the amount of meals and increase the satisfaction after meals. There are many ways to slow down the meal, such as adding a pause in the middle, reducing the volume of each bite of food and increasing the number of chews. A study among men in China shows that chewing 40 times before swallowing can reduce the amount of meals by 11.9% compared with chewing 15 times.

  3. Appropriately increase the intake of protein. High-protein foods make people feel fuller than foods rich in carbohydrates, thus suppressing appetite. This minimal effect on hunger helps to reduce the overall energy intake. High-protein foods mainly include four categories: meat (poultry, livestock, fish and shrimp, etc.), eggs, milk and soybeans.

  4. Appropriately increase dietary fiber intake. Dietary fiber is easy to produce satiety, and at the same time, it can slow down the emptying speed of food in the stomach and maintain a longer satiety. Foods rich in dietary fiber include oats, corn, sweet potatoes, whole wheat bread, green leafy vegetables and low-sugar fruits. Oats, corn and sweet potatoes can be used to replace polished rice flour and whole wheat bread instead of ordinary bread in food collocation.

  5. Reasonable eating order. Eat the big one first, then eat the small one; Eat liquid first, then eat solid; Eat low-calorie food first, then high-calorie food. Vegetables are large and low-calorie foods and should be eaten in front; Soups are easy to feel full and can be drunk before meals; Meat and staple food are high in calories and can be eaten at the back.

  6. Healthy drinking water. It is suggested that you can choose boiled water, light tea, etc., and refuse sugary drinks and juice. Because fruit juice has high sugar content and good taste, it is easy to "drink addiction" and drink too much, which is not conducive to controlling calorie intake.

Encourage 2.5 days of flexible rest to stimulate consumption experts to evaluate this.

  With the epidemic under control, the passenger flow in Taikooli, Chengdu slowly resumed photography.

  "Encourage the implementation of a flexible working system of 4.5 days a week and 2.5 days on weekends." Since March, Jiangxi, Zhejiang and other places have taken measures to actively guide cadres and workers to go out for leisure holidays on weekends, in order to boost consumption, promote economic growth and reduce the impact of the COVID-19 epidemic on the economy.

  On March 25th, Wang Qiyan, a professor at Renmin University of China and director of China Leisure Economy Research Center, said in an interview with Chengdu Business Daily-Red Star News reporter that the income of employees in government agencies, enterprises and institutions is relatively stable, and the flexible working system is pioneered by this group. It is undoubtedly a feasible practice to promote consumption and drive a wider range of consumer groups by increasing the supply of time. Su Hainan, a special researcher in china association for labour studies, is more cautious. He said that the first thing to do to resume production at present is to ensure safety and prevent the epidemic from rebounding.

  Five years ago, a 2.5-day weekly holiday was introduced.

  But the implementation effect is not ideal.

  On March 19th, Jiangxi Provincial People’s Government issued "About laying a good ‘ Combination boxing ’ Notice to boost tourism consumption. " It is mentioned that all localities and units should optimize their work arrangements according to the actual situation. In the second quarter of this year, they will try out 2.5 days of flexible work and rest on weekends and actively guide cadres and workers to go out for leisure and vacation on weekends. The working hours reduced by flexible work and rest can be compensated by extending the length of other working days.

  Recently, the "Implementation Opinions of the General Office of the People’s Government of Zhejiang Province on Boosting Consumption and Promoting Stable Economic Growth" issued by Zhejiang Province mentioned that it encourages the implementation of a 4.5-day flexible working week and supports qualified organs, social organizations, enterprises and institutions to implement the paid vacation system.

  In fact, encouraging the implementation of flexible working system is nothing new. In the Opinions of the General Office of the State Council on Further Promoting Tourism Investment and Consumption issued in August 2015, it is mentioned that flexible work and rest are encouraged, and places and units with conditions can optimize and adjust summer work and rest arrangements according to the actual situation, creating favorable conditions for employees to go out for leisure and vacation on Friday afternoons and weekends. Since then, more than 10 provinces, including Hebei and Chongqing, have issued opinions to encourage flexible work and rest for 2.5 days, but after five years, the implementation effect is not ideal.

  Why is it difficult to implement?

  Experts say that labor efficiency is relatively low.

  The reason is that Wang Qiyan, a professor at China Renmin University and director of China Leisure Economy Research Center, believes that in the final analysis, the labor efficiency is relatively low.

  Regarding the voice on the Internet that "two weekends are difficult to implement, not to mention flexible working system", Wang Qiyan believes that if society wants to make progress, there will always be some people who have to sacrifice, such as those who stand at the forefront of science and technology. There are still some groups, because of the characteristics of the industry or the particularity of the occupation, who can’t reach the average rest standard, which is also a reality.

  4.5-day flexible working system

  How much effect does it have on stimulating consumption?

  From the perspective of stimulating consumption, Su Hainan thinks that the effect is not necessarily great.

  He said that industries with relatively high wages and relatively stable incomes are willing to spend if they are given more rest time under safe circumstances. But for many employees of small and medium-sized enterprises, especially migrant workers, the first consideration may not be how to spend, but how to earn money quickly and maintain a normal life.

  Su Hainan suggested that consumption should be gradually restored while ensuring safety. In the process of restoring consumption, people must be isolated according to the relevant requirements and regulations of epidemic prevention, and retaliatory consumption in crowded places is not advocated, because there are still risks. "Don’t look at the possibility that the turnover has come up, but if there is another infection in Covid-19, it will be terrible."

Double 11 carefully buys joint health care products: the formula is changed at will, and the effect is not as good as placebo.

Original: Shi Juan returns to the park

As double 11 approaches, many people have already filled their shopping carts with health care products in advance, just waiting for the zero discount time to start shooting. Among them, one of the hottest and most publicized commodities is probably imported joint health care products. However, the latest research proves that the key ingredients in joint health care products may not be as useful as placebos. At the same time, because its formula changes at will, its medicinal properties and toxicity are also difficult to monitor. Friends who want to buy such health care products at special prices need to think twice before you do.

Today’s two articles bring together some kinds of goods that should be bought carefully or even not. Among them, the e-cigarettes that we strongly warned about were completely removed from Taobao and Tmall on November 6. So far, the online sales platform has completely banned the sale of e-cigarettes.

Writing | Shi Juan

Maybe you exercise a lot, maybe you need to sit still for a long time because of your work, or maybe you are old. In either case, the concept of protecting your joints must be familiar.

Known as a health care product that is good for joints, the most popular brand at present is Move Free, which is a brand of Schiff, a famous American health care company. Common models are as follows:

Image from Schiff official website

Costco, a famous American supermarket, also has several kinds that people often buy.

Image from CVS official website

The main components of these drugs are glucosamine and chondroitin sulfate. Some of them are added with vitamin D or an organic sulfur compound: dimethyl sulfone (MSM, an essential substance for human collagen synthesis).

Glucosamine claims to "strengthen, protect and rebuild joints", while chondroitin sulfate "can help lubricate and cushion joints", thus finally relieving joint pain, joint stiffness and arthritis.

I believe everyone has read many online articles recommending this health care product (the screenshot is omitted here).

However, are glucosamine and chondroitin sulfate really good for joints?

One study after another published in authoritative magazines shows that glucosamine and chondroitin sulfate health care products have no effect on joints. Even in the United States, there are several class actions, accusing the manufacturers of these health care products of making false advertisements, misleading and deceiving ordinary consumers [1, 2].

Photo: In June 2019, consumers collectively sued Schiff Move Free for false advertising and formally filed a case. [2]

A series of studies, the answer is getting clearer and clearer.

The most famous research is called Gait (Glucosamine/Chondroitin Arthritis Intervention Trial), which took four years and cost $12.5 million. It was funded by two departments under the National Institutes of Health (NIH), namely National Center for Complementary and Alternative Medicine (NCCAM) and National Institute of Arthritis/Musculoskeletal/Dermatology (NIAMS).

The purpose of this study is to determine whether glucosamine and chondroitin sulfate are effective in the treatment of osteoarthritis.

Let’s take out these studies and analyze them for everyone.

one

This study was published in the authoritative medical journal New England Medicine in 2006 [3].

A total of 1583 patients with osteoarthritis were recruited and randomly assigned to take:

Placebo (the same shape as medicine, but without the ingredients of medicine, it can be simply understood as sugar ball)

1,500 milligrams of glucosamine per day

1200 mg chondroitin sulfate per day

1500 mg glucosamine +1200 mg chondroitin sulfate per day

200 mg of prescription drug celebrex (an analgesic used to relieve pain for arthritis and other diseases) every day.

It is worth noting that this dose is the dose of glucosamine and chondroitin sulfate in popular health care products at that time. It is emphasized here that there was a reason for the dose in health care products at that time, which will be further explained later.

If the patient feels that the joint pain is still uncontrollable, he can take up to 4000 mg of acetaminophen (the main component of Tylenol) every day.

The main purpose of the study is to see if the pain in the knee joint is reduced by 20% after taking the medicine for 24 weeks.

The result is as follows:

It can be seen that there is no significant difference between the group taking glucosamine and chondroitin sulfate and the placebo group.

However, it is worth noting that at 24 weeks, 60.1% (more than half) people who took placebos also felt that their symptoms had improved. This extraordinary placebo effect is often seen in clinical trials of arthritis. Without knowing what they are eating, patients think they are taking useful drugs, and strong psychological hints will make the pain less intense.

Source: The-Science-Site.com.

This trial is a good example to explain why clinical trials are rigorous only if they are randomized and double-blind. Randomized double-blind trials should make sure that there is basically no difference in appearance between the pills in the placebo group and the real pills. The people who eat them can’t guess what they are eating at all, and the people who collect data don’t know what each patient is eating, so as to ensure that there will be no bias in the data collection process.

After taking celebrex for 24 weeks, those who felt that their pain was reduced by 20% were about 10% higher than those in the placebo group, achieving a statistically significant effect. Once again, it proves that this prescription drug is effective.

Finally, the author of this study divided the patients into groups according to the severity of symptoms, and found that the combined therapy of 1500 mg glucosamine and 1200 mg chondroitin sulfate/day seems to have certain effect on patients with severe symptoms. However, it is worth noting that the number of volunteers with severe symptoms in this study is relatively small, and the sample size is too small to be conclusive, which needs further research to confirm.

2

So, these authors continued to study. The new results were published in the journal Arthritis and Rheumatism in 2008 [4]. We call it study 2 (the last one was called study 1).

The time of the second study was extended from 24 weeks to 24 months (two years), and the patients with severe symptoms were studied emphatically, because the last short-term trial found that the combination therapy of glucosamine and chondroitin sulfate might be useful for these patients.

572 patients with moderate or severe knee osteoarthritis were recruited and randomly divided into five groups:

placebo

Glucosamine (500 mg each time, 3 times a day: 1500 mg/day)

Chondroitin sulfate (400 mg each time, 3 times a day: 1200 mg/day)

Glucosamine (500 mg each time, 3 times a day)+chondroitin sulfate (400 mg each time, 3 times a day)

Celebrex (200 mg once a day)

The final effective index of this experiment is not the subjective pain feeling in the first experiment (this kind of patient’s feeling is the most prone to error), but the change of joint space width is determined by X-ray at 24 months. The more severe osteoarthritis is, the more cartilage loss is, and the smaller joint space is. If a drug can stop or even reverse the shortening of joint space, it can improve the joint structure and relieve symptoms.

Finally, in the second study, the average joint spacing of patients with osteoarthritis in the placebo group decreased by 0.166 mm after two years, which meant that osteoarthritis was aggravated.

Compared with placebo, glucosamine, chondroitin sulfate or their combination therapy did not significantly reduce the loss of joint space width (arthritis did not relieve).

The researchers even observed that the joint space shortening (arthritis aggravation) of combined therapy was more serious than that of other groups, probably because taking two drugs at the same time affected the absorption of each drug-and most health care products on the market mixed these two ingredients together.

three

The final result of the GAIT study was published in Rheumatology Annual Report in 2010 [5]. We call it study three.

The third study was similar to the first study, except that the experiment was extended from 24 weeks to 24 months.

This time, the researcher recruited 662 volunteers with moderate to severe osteoarthritis and randomly divided them into five groups as in the second paper. The main index is, as in the first study, to see whether the pain of knee joint is reduced by 20% compared with that before taking medicine.

The results of this long-term experiment are similar to those of study 1. All groups had significant pain and functional improvement within 2 years. However, no treatment is significantly better than placebo. There was no statistically significant difference between the treatment groups, which once again proved the powerful placebo effect.

The good news is that no serious side effects were observed in all the treatment groups-it seems that these drugs are safe to take for at least two years in this experiment.

GAIT research tells us:

1. The curative effect of glucosamine and chondroitin sulfate comes from strong psychological suggestion to a great extent. Even if you eat "sugar balls", if you think you are eating drugs that are useful for joints, more than half of people will feel that joint pain is reduced.

2. Taking glucosamine and chondroitin sulfate at the same time may affect the absorption of any single component.

3. Glucosamine and chondroitin sulfate can not improve the shortening of joint space after illness.

four

The latest study on glucosamine and chondroitin sulfate was completed in 2016 [6]. This experiment recruited 164 patients with knee pain caused by osteoarthritis, and half of them took glucosamine (1500 mg/day) and chondroitin sulfate (1200 mg/day). The other half took a placebo.

However, the study was terminated early for an unusual reason: compared with the placebo group, the symptoms of patients who took glucosamine and chondroitin sulfate worsened.

Further than the previous three experimental results, this result suggests a terrible possibility: taking glucosamine and chondroitin sulfate may make the joint condition worse than doing nothing.

Move Free, hepatotoxicity?

I often hear friends around me say that most people eat health care products without any side effects. What if they eat them? If you don’t eat, don’t you miss that "one thousand" opportunity?

However, have you overlooked the "one thousand" harmful situation?

In fact, there are no published prospective studies on the efficacy, tolerance and safety of most health care products.

Remarks:

Prospective study usually involves observing a group of subjects for a long time, and studying whether some observed results (such as illness) are related to other factors (such as suspicious risks or protective factors) during the trial. The prospective study related to the safety of health products mentioned here is to observe whether a group of people who eat health products will have some adverse reactions related to eating health products.

This is because the ingredients of health care products are not strictly monitored by FDA, and the formula can be changed frequently. This not only makes it difficult to study its security, but also means that its security is even more insecure. Who knows which batch of formula will go wrong?

Take the current Schiff Move Free series products as an example.

If you look closely at the website of Schiff Nutrition International, the manufacturer of Move Free, you will find that there is a small line below:

“Our packaging and/or formulas change from time to time. Please refer to the actual packaging for current product information.”

Our packaging and/or formula will change from time to time. Please refer to the actual packaging for current product information. "

Figure: Composition description of a Move Free product on Schiff Nutrition International website.

At present, many cases have been reported, saying that patients taking Move Free have obvious liver damage in clinic.

In 2010, the first case report on liver injury caused by taking Move Free was published in the United States [7]. Subsequently, new cases were reported in August 2012 and September 2013. In these published cases, patients developed acute hepatocyte injury within 1-3 weeks after taking a Move Free product. The degree of injury is moderate and can be relieved within 1 to 2 months after stopping taking it; There is no immune allergy and autoimmune reaction, and it can finally recover completely in all cases. However, one patient resumed using the product when he was half well, and immediately developed acute liver injury with similar symptoms. In addition, although no more cases have been published, there are three prospective studies on drug-induced hepatotoxicity in the United States, all of which mentioned acute liver injury cases related to Move Free, all of which occurred in 2012-2013 [October 12].

The specific Move Free products mentioned in these cases at that time, in addition to the main glucosamine and chondroitin sulfate, also contained a patented herbal mixture, including China Scutellaria baicalensis and Acacia catechu.

These reports attributed the liver injury caused by Move Free to Scutellaria baicalensis Georgi in China [13], and only one case was attributed to glucosamine [11]. However, China Scutellaria baicalensis Georgi protects the liver in animal models, but not damages it [14-16]. Why can it cause human liver injury? The report did not reasonably explain its mechanism of liver injury. There is also a kind of explanation that the China Scutellaria baicalensis Georgi in Move Free contains pollutants, or maybe it is not China Scutellaria baicalensis Georgi at all (the manufacturer made a mistake and added a similar plant as China Scutellaria baicalensis Georgi).

Therefore, it is still uncertain what specific components may cause liver injury. Manufacturers often change the composition and concentration of health care products, so it is not certain whether the products currently on the market still contain these harmful ingredients. At present, Move Free series products no longer list "including China Scutellaria baicalensis Georgi and other herbal ingredients", but give a patented ingredient with a new name on some products, which is called "uniflex (fruitex-b calcium fruitoborate)", claiming to be a mineral extracted from vegetables and fruits.

What’s more noteworthy is that the content of chondroitin sulfate in the Move Free series products listed on the official website in the United States has been greatly reduced (see the figure below), and the dosage has been reduced from 1200mg per day to 200mg per day. There is no glucosamine and chondroitin sulfate in the Move Free Ultra series products, one of which only contains calcium and calcium borate, and the other contains a patented cartilage mixture. However, most of them are produced by different manufacturers, such as similar products of Kirkland brand sold by Costco, and the dosage is still 1500 mg of glucosamine and 1200 mg of chondroitin sulfate every day.

Figure: The ingredients of four existing Move Free series products (from official website, USA) are chondroitin sulfate content in the red box. Click to see a bigger picture.

Figure: Components of four existing Move Free Ultra series products (from official website, USA).

In addition, a small study in 2013 found that taking glucosamine may increase the risk of glaucoma, which will threaten vision if it is not treated in time [17]. Chondroitin sulfate can play the role of blood anticoagulant, so it may cause internal bleeding.

Another problem that is often overlooked is drug interaction: any combination of compounds may produce bad interactions. If you are taking other drugs, you must decide carefully whether to take health care products. Because they may not contain the amount indicated on the label, or they may contain pollutants-this will make it more difficult for you to accurately judge whether there will be drug interactions.

Other side effects of glucosamine and chondroitin sulfate include:

Heartburn, heartburn

feel tired and sleepy

headache

Allergic reaction (especially if you are allergic to shellfish)

What drugs/treatments are there for arthritis?

So far, there is no therapy or medicine that can cure arthritis.

There are many drugs that can be used to improve symptoms (mainly to relieve pain) and slow down the deterioration of the disease, but they cannot completely reverse the structural damage.

Because there are more than 100 different kinds of arthritis, each specific type of treatment is not exactly the same. We should prescribe the right medicine after diagnosis.

After the doctor looked around and guessed the type of arthritis he might have, there were two main methods for further diagnosis:

1. Body fluid analysis. Analyzing blood, urine and joint fluid can help determine what type of arthritis you may have. In order to obtain a sample of joint fluid, doctors usually need to put a needle into the joint space to suck some fluid.

2. Imaging analysis. Commonly used imaging methods include X-ray, CT, magnetic resonance imaging (MRI) and ultrasound.

After confirming the type of arthritis, you may need to try several different treatments or combinations of treatments to find the one that suits you best.

There are usually three types of therapies: drugs, physical therapy and surgery.

01

medicine

Different types of arthritis, should use different drugs. Commonly used arthritis drugs include:

Analgesics These drugs help to relieve pain, but they can’t diminish inflammation. For example, acetaminophen (the main component of Tylenol), Ultram (Ultracet), and some strictly regulated painkillers (such as oxycodone).

Non-steroidal anti-inflammatory drugs (NSAIDs). These drugs can relieve pain and diminish inflammation at the same time. Over-the-counter NSAID include ibuprofen (Motrin) and naproxen sodium (Aleve). Some types of NSAID must be obtained by prescription. Oral NSAID may cause stomach upset, and some may increase the risk of heart attack or stroke. Some NSAID can also be rubbed on joints as creams or gels. I have talked about the points for attention in the use of Tylenol and Ibuprofen before. If you are interested, you can go and see it (→ How to use Tylenol and Ibuprofen correctly? | 117 threesome).

Anti-irritant Some kinds of ointment contain menthol or capsaicin. Rubbing these ointments on the skin of painful joints may interfere with the transmission of pain signals, thus achieving the effect of relieving pain.

Antirheumatic drugs. Usually used to treat rheumatoid arthritis, it can slow down or prevent the immune system from attacking joints. Such as methotrexate (Trexall) and hydroxychloroquine.

Specific immune response modulators. It is usually used with anti-rheumatic drugs, which target certain protein molecules involved in immune response. Such as etanercept (Enbrel) and infliximab (Remicade).

Corticosteroids. These drugs, including prednisone and cortisone, can reduce inflammation and suppress the immune system. Corticosteroids can be administered orally or directly into joints.

02

physiotherapy

Physical therapy is helpful for some types of arthritis. Moderate exercise can improve and strengthen the muscles around the joints.

03

operation

If nothing works, it will be operated. Include joint repair or joint replacement.

04

Acupuncture, yoga, Tai Ji Chuan and massage.

There is little data to support these unconventional treatments, but there is no conclusive evidence that they are ineffective. You can look at your own reaction to see if you try.

Total knot

Although there is no convincing data to prove that health products containing glucosamine and chondroitin sulfate are beneficial to joints, many people will buy and take them. Some people think that even if there is no effect from the overall data of the population, it may be useful for individuals because of some factors; Others believe that even if most of the effects come from the placebo effect, the benefits of the placebo effect are real and hard to give up.

However, the latest clinical results and several cases of side effects show that these health care products may also be harmful to health. Manufacturers often change the formula, and the actual ingredients and dosage may be far from what you expected.

Most types of arthritis are chronic and will affect life-long diseases. Knowing all kinds of risk factors (including obesity, sedentary lifestyle, eating habits, joint injuries, smoking, etc.), changing lifestyle and reducing the chance of getting sick are the best preventive measures. It is absolutely unacceptable to put all your hopes on health care products without fundamentally changing your living habits.

references

[1] https://topclassactions.com/lawsuit-settlements/consumer-products/supplements/900914-move-free-supplement-buyers-get-class-cert-false-ad-lawsuit/

[2] https://topclassactions.com/lawsuit-settlements/lawsuit-news/791647-schiff-move-free-class-action-says-joint-health-supplements-dont-work/

[3] D. O. Clegg et al., Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 354, 795-808 (2006).

[4] A. D. Sawitzke et al., The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/ chondroitin arthritis intervention trial. Arthritis Rheum 58, 3183-3191 (2008).

[5] A. D. Sawitzke et al., Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Ann Rheum Dis 69, 1459-1464 (2010).

[6] J. A. Roman-Blas et al., Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impai rment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Arthritis & Rheumatology 69, 77-85 (2017).

[7] S. A. Linnebur, O. C. Rapacchietta, M. Vejar, Hepatotoxicity associated with chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. Pharmacotherapy 30, 750, 258e-262e (2010).

[8] L. Yang, A. Aronsohn, J. Hart, D. Jensen, Herbal hepatoxicity from Chinese skullcap: A case report. World J Hepatol 4, 231-233 (2012).

9. R. Dhanasekaran, V. Owens, W. Sanchez, Chinese skullcap in move free arthritis supplement causes drug induced liver injury and pulmonary infiltrates. Case Reports Hepatol 2013, 965092-965092 (2013).

[10] V. J. Navarro et al., Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology (Baltimore, Md.) 60, 1399-1408 (2014).

[11] S. Rossi, V. J. Navarro, Herbs and Liver Injury: A Clinical Perspective. Clinical Gastroenterology and Hepatology 12, 1069-1076 (2014).

[12] N. Chalasani et al., Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study. Gastroenterology 148, 1340-1352.e1347 (2015).

[13] V. J. Navarro, L. B. Seeff, Liver Injury Induced by Herbal Complementary and Alternative Medicine. Clinics in Liver Disease 17, 715-735 (2013).

[14] Q. Dong et al., Scutellaria baicalensis Georgi extract protects against alcohol?induced acute liver injury in mice and affects the mechanism of ER stress. Mol Med Rep 13, 3052-3062 (2016).

[15] J. Boer et al., Protection against aflatoxin-B-1-induced liver mutagenesis by Scutellaria baicalensis. Mutation research 578, 15-22 (2005).

[16] H. N. Thanh et al., Ethanol extracts of Scutellaria baicalensis protect against lipopolysaccharide-induced acute liver injury in mice. Asian Pacific Journal of Tropical Biomedicine 5, 761-767 (2015).

[17] R. K. Murphy et al., Oral Glucosamine Supplements as a Possible Ocular Hypertensive Agent. JAMA Ophthalmology 131, 955-957 (2013).

The pen name is "Cats at My Will" and now lives in Boston, USA. I graduated from the Department of Biological Sciences and Technology in Tsinghua University with a bachelor’s degree, and joined a multinational well-known pharmaceutical company to engage in drug research and development after obtaining a doctorate in the United States. For more than ten years, he led the team to fight diabetes and muscular dystrophy. In recent years, he focused on the research and development of anti-aging drugs. Personal WeChat WeChat official account "Feel Free" to talk to you about medical care.

Shi Juan

END

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Original title: "double 11 carefully buys joint health products: the formula is changed at will, and the effect is not as good as placebo | 117 threesome"

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